EVALUASI KRIM DENGAN VARIASI KONSENTRASI EKSTRAK BIJI LADA HITAM (Piper nigrum L.)

  • Senny Listy Kartika Falestin Prodi Farmasi, Sekolah Tinggi Ilmu Kesehatan IKIFA
  • Pra Panca Bayu Chandra Prodi Farmasi, Sekolah Tinggi Ilmu Kesehatan IKIFA
  • Nia Lisnawati Prodi Farmasi, Sekolah Tinggi Ilmu Kesehatan IKIFA
  • Mega Efrilia Prodi Farmasi, Sekolah Tinggi Ilmu Kesehatan IKIFA
  • Pricillya Maria Loimalitna Prodi Farmasi, Sekolah Tinggi Ilmu Kesehatan IKIFA
  • Indah Nur El Hasanah Prodi Farmasi, Sekolah Tinggi Ilmu Kesehatan IKIFA
  • Yulius Evan Christian Prodi Farmasi, Universitas Katolik Indonesia�Atma�Jaya

Abstract

Black pepper (Piper nigrum L.) is a medicinal plant that contains active compounds such as piperine, flavonoids, and essential oils, which are known to exhibit anti-inflammatory, antioxidant, and antimicrobial properties. This study aims to evaluate the physical quality of cream formulations containing varying concentrations of 96% ethanol extract of black pepper seeds. A descriptive experimental method was employed, focusing on the assessment of organoleptic properties, homogeneity, pH, spreadability, adhesion, and viscosity over a four-week storage period. Four formulations were tested: F0 as a control without extract, F1 with 1% extract, F2 with 2%, and F3 with 3%. The evaluation results showed that all formulations met the required physical quality standards. The creams retained stable color and odor, demonstrated uniform ingredient distribution, and had pH values within the safe range for topical application (4.56.5). The spreadability and adhesion properties were within ideal criteria, and viscosity levels ranged between 2000 and 5000 cP, indicating suitable consistency. Among the tested formulations, F2 exhibited the most optimal performance in terms of physical stability and user comfort. Based on these findings, it can be concluded that black pepper seed extract is suitable for formulation into a topical cream preparation, with the 2% concentration showing promising potential for development as a natural-based, safe, and effective topical product.

Published
2025-12-10