2026-05-16T21:05:24Z https://jurnal.stiksam.ac.id/index.php/jim/oai

oai:ojs.jurnal.akfarsam.ac.id:article/1 2017-01-25T09:45:44Z jim_akfarsam:ART

oai:ojs.jurnal.akfarsam.ac.id:article/3 2017-01-25T09:45:44Z jim_akfarsam:ART

oai:ojs2.jurnal.stiksam.ac.id:article/4 2021-01-31T08:19:32Z jim:ART

UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN KECOMBRANG Etlingera elatior (Jack) R.M.Sm TERHADAP Salmonella typhi Kusumawati, Eko Supriningrum, Risa Rozadi, Reza kecombrang (Etlingera elatior) identification secondary metabolites antibacterial Farmakognosi Research Test Antibacterial Activity of Ethanol Extracts of Leaves kecombrang against Salmonella typhi aims to determine the antibacterial activity of ethanol extract of leaves kecombrang against Salmonella typhi. The extract used is kecombrang leaf extract prepared by maceration using ethanol 95%, extracts obtained test chemical classes of compounds to determine the content of the active compound. Antibacterial activity test conducted at five concentrations of the extract is 20%, 40%, 60%, 80%, and 100%. Inhibition zone measurement results are then analyzed using One Way ANOVA with SPSS 20 to determine whether there is a difference at each concentration. The results showed kecombrang leaf ethanol extract 20%, 40%, 60%, 80%, and 100% produce inhibition zone diameter 3.9 mm; 6.5 mm; 6.75 mm; 7:45 mm; and 9:28 mm, 0 mm for the negative control and positive control 32.61 mm. The test results show the class of secondary metabolites kecombrang leaf ethanol extract contains tannin, saponin, and flavonoids. Of statistical tests concluded there were significant differences of treatment results in inhibition of the respective concentrations of ethanol extracts of leaves kecombrang Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-25 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/4 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung; 1-7 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 1 (2015): Jurnal Ilmiah Manuntung; 1-7 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/4/3 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/5 2021-01-31T08:19:35Z jim:ART

STUDI FARMAKOVIGILANS PENGOBATAN ASMA PADA PASIEN RAWAT INAP DI SUATU RUMAH SAKIT DI BOJONEGORO Lorensia, Amelia Amalia, Ratna Ayu asthma adverse drug reactions drug interaction pharmacovigilance Farmakologi Background: Asthma is a respiratory disease with a large enough number of prevalence in the world. Asthma treatmentin hospital needs serious monitoring because of the risk to patient safety and increase the cost of treatment. One attempt to reduce the incidence of unwanted is the pharmacovigilance studies to improve patient safety.Purpose: to determine safety in terms of adverse drug reactions (ADR) and drug interactions of the treatment of inpatient asthmatic patients in a hospital.Methods: This is a non-experimental study with sampling using purposive sampling. Then the data were obtained from medical records were analyzed ADRs and drug interactions that occur using the library and shown descriptively.Results: The study sample as many as 43 people. The results showed there were 56 cases of ADRs on asthma medications, especially the use of nebulized salbutamol (57.14%). While the incidence of asthma therapy drug interactions there were 10 cases and the highest is aminophylline with salbutamol (14.29%).Conclusion: Treatment of asthma need to get to the ADR incidence and risk of drug interactions. Incidence of ADRs and drug interactions at most of the use of salbutamol which is relatively safe preference. This still needs to be done further research. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-25 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/5 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung; 8-18 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 1 (2015): Jurnal Ilmiah Manuntung; 8-18 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/5/4 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/6 2021-01-31T08:19:36Z jim:ART

Hubungan Lingkungan Fisik dan Tindakan PSN dengan Penyakit Demam Berdarah Dengue di Wilayah Buffer Kantor Kesehatan Pelabuhan Kelas II Andi Anwar, Adi Water shelter humaditity eraclication of mosquito breeding Dangue hemorrhagic faver (DHF) Kesehatan Masyarakat Dengue Hemorrhagic Fever (DHF) is a health problem in Indonesia, which can lead to the extraordinary events (plague).The development of science and technology affect the development of social and cultural, agricultural, industrial, mining and public mobility. The second-class Port Health Office Samarinda is included as endemic area; with the 33 total numbers of cases in 2013 and there were 20 cases started from January to August 2014. The purpose of this study was to find out the relationship between water shelter, humidity and eradication of mosquito breeding toward DHF in buffer area of the Second-Class Port Health Office Samarinda. This type of research is an analytical survey method with cross sectional approach. It is included as the research which learns the dynamics of the correlation between risk factors and effects, using observation or data collection approach at once.  The sample of this study was 140 respondents with observation and measurement using Mann Whitney and Chi Square tests. Variables of this study consisted of dependent variable, which is DHF and independent variables are the water shelter, humidity and eradication of mosquito breeding. The findings showed there was relationship between water shelters (ρ value0,031), and humidity (ρ value0,046), and also eradication of mosquito breeding (ρ value0,000). Based on the results of this study, it is expected to the healthcare institutions to give frequent health education to the society about the dangers of DHF, control the breeding of mosquitoes, and prevent mosquitoes’ bites in order to prevent infected by this disease. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-25 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/6 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung; 19-24 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 1 (2015): Jurnal Ilmiah Manuntung; 19-24 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/6/5 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/7 2021-01-31T08:19:37Z jim:ART

PENETAPAN KADAR ASAM LEMAK BEBAS DAN BILANGAN PEROKSIDA PADA MINYAK GORENG YANG DIGUNAKAN PEDAGANG GORENGAN DI JL. A.W SJAHRANIE SAMARINDA Nurhasnawati, Henny free fatty acids peroxide value cooking oil Kimia Free fatty acids and peroxide are part of cooking oil quality parameters. This study aims to determine the levels of free fatty acids and peroxide value in cooking oil used by fried merchant in Jl. A.W. Sjahranie Samarinda. Sampling was done by total sampling which is cooking oil before frying and after frying a few times from four fried merchants. Determination of free fatty acid content using alkalimetry method and levels of peroxide using iodometric method.The test results of the free fatty acid content of samples A, B, C, D cooking oil before frying is equal to 0.16%; 0.27%; 0.33%; 0.32%, and free fatty acid levels after few times frying is 0.19%; 0.29%; 0.37%; 0.36%. The test results of the peroxide sample A, B, C, D cooking oil before frying in the amount of 18.95 meq O2/kg; 27.63 meqO2/kg; 24.67 meq O2/kg; 23.29 meq O2/kg. Peroxide levels after several times frying is 26.25 meqO2/kg; 35.72 meqO2/kg; 34.54 meqO2/kg; 33.16 meqO2/kg. Average levels of free fatty acids cooking oil before frying is 0.27% and after frying to 0.30%, or an increase of 12.04%. While the average level of peroxide cooking oil before frying of 23.64 meqO2/kg and after frying be 32.42 meqO2/kg or an increase of 37.16%. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-25 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/7 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung; 25-30 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 1 (2015): Jurnal Ilmiah Manuntung; 25-30 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/7/6 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/8 2021-01-31T08:19:40Z jim:ART

FORMULASI GELHAND SANITIZER DARI KITOSAN DENGAN BASIS NATRIUM KARBOKSIMETILSELULOSA Supomo, Supomo Sukawati, Yullia Basyar, Fredi Citosan Gel Hand Sanitizer Farmasetika Chitosan has been widely used in industrial, food, pharmaceuticals and agriculture. Chitosan is a natural biocompatible polymers means that as nature does not have the side effect, non-toxic, can not be easily digested and broken down by microbes (biodegradable). This study aims to determine whether the chitosan may be formulated into dosage gel hand sanitizer that meets the requirements of the physical stability of the gel.Chitosan is formulated with 3 varying concentrations of Na CMC basis of 3%, 4.5% and 6%. Tests conducted gel formulation is the physical stability test which includes organoleptic test, homogeneity, pH test, test dispersive power, viscosity test and test consistency. Testing is done every week for 4 weeks of storage.Results of testing physical properties of chitosan gel hand sanitizer has the shape and color stable but the resulting aroma change during storage. pH gel meet the requirements, the consistency test of phase separation does not occur, the homogeneity test showed no homogeneous gel, gel dispersive power does not meet the requirements, the viscosity of the gel preparation third formula does not meet the requirements of viscosity gel Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/8 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung; 31-37 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 1 (2015): Jurnal Ilmiah Manuntung; 31-37 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/8/7 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/9 2021-01-31T08:19:42Z jim:ART

HUBUNGAN KERJASAMA DAN IMBALAN DENGAN KINERJA PEMEGANG PROGRAM PENANGGULANGAN PENYAKIT DI KOTA BALIKPAPAN Adrianto, Ratno Cooperation Benefits Performance Kesehatan Masyarakat Various activities have been implemented in the prevention and control of disease in the city of Balikpapan, but based on the Health Profile 2012 field program is known that the achievement of disease control and environmental sanitation is still not maximal. This corresponds to an increase in cases of environment-linked diseases such as DBD, tuberculosis, diarrhea, ISPA and pneumonia each year. The quality of programperformance officer holder is a factor that affects the extent of success in achieving thehealth programs that have been established.The purpose of this study was to determine the relationship between co-operation, in return, infrastructure and support superior to the performance of holders of Disease Prevention program in the city of Balikpapan. This type of research is analytic surveywith cross sectional approach. The population in this study were all employees of the holder of health programs in 27 health centers with a total sampling Balikpapan 54 people. The method used is the analysis of univariate and bivariate.The results showed no significant relationship between co-operation with the performance of the holder of the eradication program (ρ value 0.002), and betweenrewards to the performance of the holder of the eradication program (ρ value 0.027).Suggestions to increase cooperation and support employers through training soft skillsand personality, as well as leadership training management organizations, as well as considering pemberiaan remuneration policy. Thus achieving the health program can be run according to plan. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/9 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung; 38-41 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 1 (2015): Jurnal Ilmiah Manuntung; 38-41 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/9/8 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/10 2021-01-31T08:19:44Z jim:ART

EKSTRAK ETANOL DAUN SIRIH MERAH (Piper crocatum) MENURUNKAN KADAR GULA DARAH MENCIT DIABETES Siregar, Ambali Azwar Harahap, Urip Mardianto, Mardianto Piper crocatum mice diabetes aloxan lose of weight Farmakognosi Diabetes mellitus is one of desease that have a large population and trend to increase. sulfonylurea and biguanide are almost used treatment but have unexpected side effects. The research still necessary to seek alternative medicine, such as Piper crocatum.This study aimed to determine the effect of ethanol extract of red betel leaves on blood sugar levels and body weight of mice (Mus musculus L.) diabetes. This riset was started to produce simplicia and drilled become powders, continued extract with 70% ethanol. The extract was evaporated with rotary evaporator until obtaine crude extract. And then screen it that determine phytochemical. To continued test on tolerance of level of glucose then mice diabetes induced aloxan.In summary, extract of red betle ethanolic has contained alkaloid, quercetin flavonoid, steroid and fenolic compounds and decreased level of glucose in blood mice diabetes. Besides, it can reduce lose of weight symptom. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/10 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung; 42-46 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 1 (2015): Jurnal Ilmiah Manuntung; 42-46 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/10/9 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/11 2021-01-31T08:19:47Z jim:ART

OPTIMASI FORMULA EKSTRAK JAHE MERAH (Zingiber officinale) DENGAN METODE KEMPA LANGSUNG MENGGUNAKAN ANALISIS SIMPLEX LATTICE DESIGN Sa'adah, Hayatus extract red ginger simplex lattice design direct compaction method Farmakognosi Processing of medicinal plants into the appropriate dosage form can ensure security during use. It is a motivation in making acceptable dosage form which is easy and convenient to use, especially the manufacture of ethanol extract red ginger tablets using a combination of starch 1500 and amprotab.The study begins with the manufacture of dry extract of red ginger. Optimization of making tablets using a combination of starch 1500 and disintegrator with simplex lattice design using three formulas is done by direct compaction method. Further testing on the tablet hardness, friability and disintegration time.The results showed starch 1500 has a greater influence increase hardness and disintegration time of tablets, as well as lowering the fragility of the tablet. While the interaction of starch 1500 and disintegrator has no effect on the physical tablet. The optimum proportion of the combination of starch 1500 and disintegrator meet the physical requirements of tablets with a ratio of 4: 6 with 7.99 kg hardness, the friability of 0.32% and disintegration time of 2.42 minutes Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/11 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung; 47-51 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 1 (2015): Jurnal Ilmiah Manuntung; 47-51 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/11/10 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/12 2021-01-31T08:19:50Z jim:ART

ANALISA COST OF ILLNESS AKIBAT PENGGUNAAN NSAIDS DI SEBUAH APOTEK DI KOTA MEDAN, INDONESIA Tanjung, Hari Ronaldo Sarriff, Azmi Harahap, Urip Cost of Illness NSAIDs Utilization Community Pharmacy Farmakologi Background: A drug therapy problem is any undesirable event experienced by a patient which involves, or is suspected to involve drug therapy and that interferes with achieving the desired goals of therapy. Drug Therapy Problems (DTPs) can lead to ineffective pharmacotherapy and may cause drug-related morbidity and mortality.Objective: The study aimed to estimates the direct medical cost of illness caused by the drug morbidity or mortality related to NSAID utilization in a community pharmacy setting at Medan, Indonesia.Method: Thisstudy used 7 (seven) categories probabilities and costs associated with the therapeutic outcomes to estimate the direct medical cost of illness resulting from morbidity related NSAIDs utilization. Direct non medical costs, indirect costs, and intangible costs related to drug-related-morbidity and mortality were not valued in this cost-of-illness analysis.The duration of the study was from July 2009 to October 2010.Result: The patient that experienced NSAIDs-related morbidity estimated to spend Rp.467.848,- each and Rp.11.696.200,- in total to managing the morbidity. Every Rp.1,- spent on NSAIDs therapy, an additional Rp.1,45,- was estimated to spent in managing morbidity related NSAIDs utilization.Conclusion: This result showed the cost of illnessrelated morbidity of NSAIDs utilization exceeds the cost of the medications themselves Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/12 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung; 52-56 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 1 (2015): Jurnal Ilmiah Manuntung; 52-56 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/12/11 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/13 2021-01-31T08:19:53Z jim:ART

LAYANAN PESAN SINGKAT PENGINGAT MENINGKATKAN KEPATUHAN MINUM OBATPASIEN DIABETES MELITUS DI RSUD ULIN BANJARMASIN Alfian, Riza Diabetes Mellitus short message service reminder adherence blood glucose levels. Layanan Kesehatan Diabetes melitus is one ofthe metabolic disorders with characteristic hyperglycemia that occurs due to abnormal insulin secretion, insulin resistance or both. The non adherence patients of taking antidiabetic drugs are the main factors that could cause high blood glucose levels, so it is necessary an intervention to achievedoutcome therapy desired. Giving of short message service reminder intervention in diabetes mellitus patients was expected to improved the medication adherence and achieved normal blood glucose levels.This study was conducted to determine the effect of a short message service reminder on medication adherence of ambulatory diabetes melitus patients in Ulin General Hospital Banjarmasin.This study was conducted with quasi-experimental design,the data were taken prospectively during May to June, 2014. The subjects were ambulatory diabetes melitus patients in Ulin General Hospital Banjarmasin who had received oral antidiabetic drugs. Subject who met the inclusion and exclusion criteria were 39 patients and had given an intervention for seven days. The data collected by interviews and pill counting on filling sheet. The blood glucose levels data was taken from their medical records.The result showed that giving of a short message service reminder intervention improve patient adherence (p<0,05). Fasting blood glucose level and blood glucose level two hours post prandial have decreased significantly (p<0,05). There were correlation between the patient adherence and the decreasing in fasting blood glucose levels (p=0,050; r=0,316) and blood glucose two hours post prandial levels (p=0,010; r=0,040).Based on these result, it can be concluded that the giving of short message service reminder in diabetes melitus patientshas been improved patient adherence. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/13 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung; 57-61 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 1 (2015): Jurnal Ilmiah Manuntung; 57-61 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/13/12 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/14 2021-01-31T08:19:55Z jim:ART

HUBUNGAN DUKUNGAN KELUARGA DENGAN KEPATUHAN MINUM OBAT PASIEN HIPERTENSI LANSIA DI WILAYAH KERJA PUSKESMAS SUNGAI CUKA KABUPATEN TANAH LAUT Susanto, Yugo Family Support Adherence Hypertension Elderly Kesehatan Masyarakat One of communicable diseases become very serious health problem was hypertension. The purpose of hypertension therapy was to control blood pressure in range of normal blood pressure, it is needed the adherence for hypertension therapy. The family supportcould improved healthy status. Patient with family support  feel that people care, so it could directed patient to improve their healthy lifestyle.The purpose of this study was to determine elderly family support, medication adherence in elderly hypertensive patients, and analyzedthe correlation between the family support with the adherence ension in elderly hypertension patients in Puskesmas Sungai Cuka Tanah Laut.This study was conducted with the cross sectional design in December 2014 until January 2015. Population was280the elderly patient in the region of  primary public health Sungai Cuka and 164 of them were used for sample. Data was collected by completion questionnaires family support and Morisky Modification Adherence Scale (MMAS)questionnaires. Data analysis was performed by gamma test with 95% confidence level.Based on the results, that Elderly who have family support by category 23.8% lower category, middle category were 64%, high category were 11.6%, and 0.6% were very high category. The adherence degree of elderly hypertension patientwere 45,7% low adherence degree, moderate adherence degreewere 36%, and high adherence degree were 18.3%. There were a correlation between the family support andthe medication adherence in elderly hypertension patients at Puskesmas Sungai Cuka Tanah Laut. (γ =0.295). Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/14 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung; 62-67 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 1 (2015): Jurnal Ilmiah Manuntung; 62-67 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/14/13 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/15 2021-01-31T08:19:58Z jim:ART

UJI DAYA HAMBAT EKSTRAK ETANOL RIMPANG TEMU GIRING (CURCUMA HEY NEANA VAL.) TERHADAP PERTUMBUHAN ESCHERICHIA COLI SECARA IN VITRO Putra, Aditya Maulana Perdana Rustifah, Rustifah Arsyad, Muhammad Antibacterial Curcuma heyneana rhizome (Curcuma heyneana Val.) Minimum inhibitory concentrations Farmakognosi Infection is a major problem that the world’s attention. Infectious diseases have caused the death of over 13 million people worldwide every year, particularly in the developing countries such as Indonesia. One of the species of bacteria that cause infections are Escherichia coli. Curcuma heyneana rhizome (Curcuma heyneana Val.) is a plant that is often used as a traditional medicine to antibacterial. This study was intended to determine the antibacterial inhibition activity, and minimum inhibitory concentrations (MIC) from the usage of an ethanol extract in the curcuma heyneana rhizome (Curcuma heyneana Val.) for the growth of an Escherchia coli by in vitro.Curcuma heyneana rhizome (Curcuma heyneana Val.) was extracted using maseration method with solvent ethanol. Each extracts identified the active compounds group consisting of flavonoids, saponins, curcumin, volatile oil, and tannins. This study was an experimental laboratoric by using the diffusion method with discs blank with 10  treatment groups concentration which are 100%, 50%, 25%, 12,5%, 6,25%, 3,12%, 1,56%, 0,78%, positive control and negative control with three repetitions.The phytochemical screenings analysis showed curcuma heyneana rhizome (Curcuma heyneana Val.) of ethanol extract containing flavonoids, saponins, curcumin, volatile oil, and tannins. Ethanol extract in the curcuma heyneana rhizome (Curcuma heyneana Val.) had an effectiveness in inhibiting the growth of an Escherchia coli by in vitro. Minimum inhibitory concentrations (MIC) from the usage of an ethanol extract in the curcuma heyneana rhizome (Curcuma heyneana Val.) for the growth of an Escherchia coli by in vitro is 12,5% with average inhibition zone 9,77 mm. The results showed that the ethanol extract curcuma heyneana rhizome (Curcuma heyneana Val.) had an effectiveness in inhibiting the growth of an Escherchia coli, it showed inhibition zone diameter due to higher concentrations of the resistance is increasing. Analysis of the test data with Kruskal-Wallis (sig) = 0,001 which is smaller than α < 0,05. It means that there are significant differences in the average diameter of an each concentration of ethanol extract of curcuma heyneana rhizome in i Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/15 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung; 68-74 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 1 (2015): Jurnal Ilmiah Manuntung; 68-74 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/15/14 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/16 2021-01-31T08:20:00Z jim:ART

IDENTIFIKASI DAN PENETAPAN KADAR RHODAMIN B PADA KUE BERWARNA MERAH DI PASAR ANTASARI KOTA BANJARMASIN Sari, Ratih Pratiwi Rhodamine B red cake Thin Layer Chromatography Visible spectrophotometry Kimia Rhodamine B is a synthetic dye used to dye the textile industry. Rhodamine B is presence in food can cause poisoning, skin irritation, lung irritation, eye irritation, throat irritation, nasal irritation, and cause liver damage if exposed to high concentrations. Samples taken from the red cake seller in the Antasari Banjarmasin market. This research is a descriptive study. The sampling technique used was accidental sampling. Rhodamine B on a method of identification of samples using Thin Layer Chromatography and Visible spectrophotometry. Samples were prepared using the absorption method wool. The resulting solution will be used as identification in Thin Layer Chromatography using silica gel GF 254 plates with a mobile phase of n-butanol : ethyl acetate : ammonia (10:4:5). Rhodamine B assay performed visible spectrophotometry at a wavelength of 544 nm.Results of identification were putri ayu cake, Apam cake, Kukus cake A, Bolu cake, Singkong cake, and Kukus cakes B, shows that 1 positive samples containing Rhodamine B is a Apam cake. After that, the assay of Rhodamine B was performed in the sample apam  cake and obtained for 0,4229 ± 0,1157 mg of Rhodamine B in 1 piece of red cake Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/16 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung; 75-84 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 1 (2015): Jurnal Ilmiah Manuntung; 75-84 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/16/15 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/17 2021-01-31T08:20:02Z jim:ART

IDENTIFIKASI DAN PENETAPAN KADAR RHODAMIN B DALAM KERUPUK BERWARNA MERAH YANG BEREDAR DI PASAR ANTASARI KOTA BANJARMASIN Kumalasari, Eka crackers Rhodamine B Thin Layer Chromatography and UV-Vis spectrophotometry Kimia Crackers are made from tapioca flour batter mixed with flavorings and colorings, still many outstanding crackers that contain ingredients banned dye Rhodamine B. Rhodamine B is a chemical used for red dye in the textile industry and plastic. Rhodamine B can cause cancer, poisoning, lung irritation, sore eyes, and sore throat. This study aims to identify and determination the levels of Rhodamine B in circulating red crackers Antasari market Banjarmasin.The population is that sold in the red crackers that sold in Antasari market Banjarmasin.. The sampling is technique incidental sampling , that is based on chance, so any population by chance met with researchers can be used as a sample. Identification of Rhodamine B was done by Thin Layer Chromatography (TLC) by using the stationary phase silica GF 254 and mobile phase is elution solvent is n-butanol, ethyl acetate, ammonia (10:4:5). Then detected with a UV lamp 254 nm and 366 nm. While for the determination of levels using Vis spectrophotometry at a wavelength of 544 nm.The results showed that the samples of 6 found one sample containing Rhodamine B, namely samples 5 (cassava crackers matches) and obtained values of 7,25 ± 3,8640 levels mg / kg. Based on these results, Rhodamine B still found in crackers that sold in the market Antasari Banjarmasin. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/17 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung; 85-89 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 1 (2015): Jurnal Ilmiah Manuntung; 85-89 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/17/16 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/18 2021-01-31T08:20:06Z jim:ART

KARAKTERISTIKEKSTRAK AIR DAUN PUGUNTANO [Curanga fel-terrae (Lour.) Merr.] YANG BERPOTENSI SEBAGAI ANTELMINTIK Patilaya, Popi Husori, Dadang Irfan water extract leaf pugun tano FTIR Farmakognosi OBJECTIVE: This study aimed to determine the characteristics of the water extract of leaves puguntano (Curanga fel-terrae (Lour.) Merr.) Using spectroscopic methods and phytochemical screening.METHODOLOGY: phytochemical screening performed to analyze compounds alkaloids, flavonoids, glycosides, anthraquinone glycosides, saponins, tannins, cyanogenic glycosides, and triterpenoids / steroids. Analyses were performed using FTIR spectrophotometer (Shimadzu) with IR Solution software. The wavelength is set at 4000 – 400 cm-1 with a resolution of 4 cm-1 and 16 scanner.RESULTS: Puguntano leaf water extract contains flavonoids, glycosides, saponins, tannins, steroids, and terpenoids. Infrared spectrum of puguntano leaf aqueous extract showed a O – H fuctional group at 3313.71 cm-1, C – H at 2974.23 and 2881.65 cm-1, C = C at 1689.65 and 1597.06 cm-1, C – O at 1265.30 and 1076.28 cm-1 and group C – H aromatics at 813.96 cm-1 in the fingerprint region Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/18 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung; 90-93 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 1 (2015): Jurnal Ilmiah Manuntung; 90-93 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/18/17 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/19 2021-01-31T08:20:08Z jim:ART

STABILITAS DAN AKTIVITAS GEL EKSTRAK BULBUS BAWANG TIWAI (Eleutherine americana (Mill.) Urb.) SEBAGAI ANTI ACNE Warnida, Husnul Sukawaty, Yullia Mega, Mega Anti acne Bawang tiwai (Eleutherine americana) Carbomer 940 Staphylococcus epidermidis. Farmakognosi awang Tiwai has an antibacterial activity toward some microorganisms e.g. Staphylococcus epidermidis dan Propionibacterium acne, two acne related bacteria. Bawang Tiwai extract 1% and 2% were formulated into gel (no oil content, because oil could make the acne worse) with carbomer 940 as gelling agent. Physical stability of bawang tiwai gel was evaluated included stability, organoleptic, pH, homogeneity, viscosity, consistency, spreading test, and activity toward Staphylococcus epidermidis.  The result showed that all formulas are stable after 7 days. The test results of antibacterial activity gel are 17,24 mm dan gel 19,75 mm to gel 1% dan 2% respectively. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/19 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung; 94-99 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 1 (2015): Jurnal Ilmiah Manuntung; 94-99 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/19/18 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/20 2021-01-31T08:13:53Z jim:ART

UJI AKTIVITAS EKSTRAK ETANOL DAUN ALPUKAT (Persea americana Mill.) TERHADAP PENYEMBUHAN LUKA BAKAR PADA PUNGGUNG MENCIT PUTIH JANTAN (Mus musculus) Sentat, Triswanto Permatasari, Rizki Persea americana Mill burn healing back skin of mice Farmakognosi Activity Assay of avocado leaf (Persea americana Mill.) ethanol extract on burn healing at back skin of white male mice (Mus musculus) aims to determine the best concentration of avocado leaf ethanol extract to healing burn on back skin of mice. Extract of avocado leaf obtained by maceration method using ethanol 70%. Burn made by soldering iron modified with square plate (size 1 x 1 cm2), during 2 seconds contact at the skin and make the skin formed blister. Observation of the burn area was doing daily for 14 days, and also the treatment with the 3 concentrations extract variation (20%,35%, and 50%), negative control and positive control. Result of research show that all avocado leaf ethanol extract in concentrations 20%, 35% and 50% have good activity in burn healing, from first day until 14th day they showed percentage of burn recovering successively equal to 86%, 88% and 90%. Negative control showed that process healing of burn was very tardy, only has percentage of burn recovering equal to 32,67% on 14th day, while positive control showed 100% burn healing on 11st day. The best concentration of  avocado leaf ethanol extract on healing burn is 50% with 90% burn healing Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/20 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung; 100-106 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 2 (2015): Jurnal Ilmiah Manuntung; 100-106 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/20/19 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/21 2021-01-31T08:13:55Z jim:ART

FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN ASUPAN SERAT PENDERITA DM DI POLI PENYAKIT DALAM RSUD Dr. Hi. ABDUL MOELOEK PROVINSI LAMPUNG TAHUN 2014 Muliani, Usdeka Fiber in diabetic patient Kesehatan Masyarakat Indonesia is now facing degenerative diseases such as diabetes. From previous studies found fiber intake patients with DM is still much less than that recommended, while the fiber is very useful to control blood sugar levels in diabetic patient. The purpose of this study was to determine the factors associated with fiber intake in patients with diabetes mellitus disease in internist clinic Dr H. Abdul Moeloek Hospital Lampung 2014? The experiment was used analytic research by cross sectional approach, a sample of 48 respondents. Data were analyzed by univariate and bivariate. The study concluded  the most respondents: (1) age 46-65 years 66.7%; (2) 70.8% of the female sex; (3) sufficient knowledge of fiber 56.2% (4)  never received nutritional counseling; (7) 85.4% less fiber intake. From the results of the bivariate analysis found no relationship between gender, knowledge, attitudes, education, and nutrition counseling with fiber intake respondents. Relative levels for respondents with knowledge and attitude toward less fiber, and fiber intake respondents are less good then advice the authors need to increase cooperation between the clinic personnel in order to refer all patients with DM to nutrition clinic in order to obtain nutritional counseling. Other suggestions in order to do further research to find out why fiber intake of diabetic patients are still lacking, and the study of other factors such as psychological, social culture, physical state, and the state of nutrition associated with fiber intake in diabetic patient Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/21 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung; 107-113 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 2 (2015): Jurnal Ilmiah Manuntung; 107-113 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/21/20 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/22 2021-01-31T08:13:59Z jim:ART

OPTIMASI FORMULA MATRIKS KITOSAN DENGAN METILSELULOSA PADA PELEPASAN TERKENDALI SEDIAAN GRANUL TEOFILIN Suprianto, Suprianto theophylline chitosan and methylcellulose Kimia The in vitro study was carried out on the release of active ingradient theophylline from granules prepared by moist granulation method. The granule matrix was prepared from the mixture of chitosan isolated from SwaIIo shrimp (Metapenaeus monoceros) (in accordance with the Protan Laboratories, Inc standard requirement) and methylceliuiose 1500 cps. The granules were filled into 850 mg capsules containing 200 mg theophylline. The maximum weight of chitosan and methylcellulose for each capsule was determined by factorial design 22.The result showed that, when the amount of chitosan was kept constant, an increase in the amount of methylcellulose will increase the release rate of theophylline from granules. The optimum weight of chitosan and methyIceIIuIose are 609.24 mg and 20.00 mg, respectively for one capsule. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/22 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung; 114-120 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 2 (2015): Jurnal Ilmiah Manuntung; 114-120 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/22/21 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/23 2021-01-31T08:14:00Z jim:ART

FORMULASI GEL PATI BENGKUANG (Pachyrhizus erosus (L.) Urb.) DENGAN GELLING AGENT METILSELULOSA Warnida, Husnul bengkuang gel methylcellulose pachyrhizus erosus skin whitening Farmakognosi Bengkuang roots (Pachyrhizus erosus (L.) Urb.)  empirically have been used as cosmetics materials, primarily as sun screen and whitening agent. Bengkuang roots posses 6 compound which have tyrosinase inhibitory activities. Commercially, bengkuang roots available as whitening cream and lotion but those dosage forms are not suitable for oily skin. In this study the gel was formulated with varying methylcellulose (4% and 5%) as gelling agent. The evaluation included stability, organoleptic, pH, homogeneity, and spreading test. Formula A (4% methylcellulose) meets all physical requirements of gel. The result of acceptability (hedonic test. showed the most acceptance formula was formula A (4% methylcellulose). Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/23 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung; 121-126 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 2 (2015): Jurnal Ilmiah Manuntung; 121-126 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/23/22 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/24 2021-01-31T08:14:03Z jim:ART

UJI TOKSISITAS AKUT EKSTRAK ETANOL DAUN KEREHAU (Callicarpa longifolia Lam.) TERHADAP MENCIT PUTIH Siswanto, Eka Sari, Desy Nur Indah Supomo, Supomo Callicarpa longifolia Lam acute toxicity LD50 Farmakognosi Leaves kerehau (Callicarpa longifolia Lam.) is one of the plants used for the treatment of malaria, ulcers, diarrhea, treatment after delivery, and fever, by drinking boiled water. Report usage and security kerehau leaves are still very few. The purpose of this study to determine the potential for acute toxicity by determining the value of LD50 (Lethal Dose 50) in 4 dose-rise that dose I, II, III, and IV of the ethanol extract of the leaves kerehau against this mice. The Research. Pharmacologically using experimental methods using a completely randomized design pattern is undirectional in the selection of test animals, They are 25 mice were divided into five groups (5 mice each group), with observed 4 hours to determine the toxic symptoms and continued observation every 24 hours for 7 days to see death. Results from this study show from 4 dose levels, dose group I = 16g / kg, group II = 8g / kg, group III = 4g / kg and group IV = 2g / kg and control = 0.5 ml Na-CMC. Symptoms namely the observation of behavior and neuromuscular but not on observations of the autonomic nervous, respiratory, gastrointestinal, and skin. LD50 value obtained is expressed by the LD50 (16g / kg) were categorized as practically non-toxic (> 15g / kg) Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/24 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung; 127-132 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 2 (2015): Jurnal Ilmiah Manuntung; 127-132 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/24/23 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/25 2021-01-31T08:14:05Z jim:ART

UJI AKTIVITAS EKSTRAK ETANOL GAMBIR (Uncaria gambir Roxb.) TERHADAP PENYEMBUHAN LUKA BAKAR PADA KULIT PUNGGUNG MENCIT PUTIH JANTAN (Mus musculus) Handayani, Fitri Siswanto, Eka Pangesti, Lintang Ayu Trisna ethanol extract of gambir burns wound surface area Farmakognosi Gambir (Uncaria gambir Roxb.) contains flavonoids, tannins, saponins and alkaloids that can help in the healing process of burns on the back skin of mice. Gambir has been used for the treatment because it has the effect of antimicrobial and anti-inflammatory. Gambir is used by the people as a traditional medicine to treat burns.This research is experimental research. The object studied is the potential of gambir extract on healing burns of mice back skin. The number of mice used are 15 which divided into 5 groups: the positive control group (branded ointment), negative control group (vaseline flavum), group of gambir ethanol extract and vaseline flavum concentration of 25%, 35%, and 45%. Each group consisted of 3 mice.Backs of the mice induced using a heated solder which tip contained stainlees plate measuring 1x1 cm and placed for 2 seconds on the back skin of mice. The percentage of burns healing is obtained by calculating the surface area of the wound. The data were analyzed using ANOVA analysis followed by LSD test. The results showed that ethanol extract of gambir concentration of 25% with the healing burns percentage of (72.00%), the concentration of 35% (85.00%), and the concentration of 45% (88.67%) have activity on healing burns of back skin of mice. The results of data analysis using ANOVA showed that the data has significant differences with a significance value <0.05 is 0.000. LSD test results stated that each treatment group have significant differences with a significance value <0.05. It can be seen that with increasing dose will be followed by duration of burns healing Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/25 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung; 133-139 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 2 (2015): Jurnal Ilmiah Manuntung; 133-139 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/25/24 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/26 2021-01-31T08:14:07Z jim:ART

PERBAIKAN PERILAKU DAN TEKANAN DARAH PASIEN HIPERTENSI DI RSUD DR. H. MOCH. ANSARI SALEH BANJARMASIN SETELAH PEMBERIAN LEAFLET EDUKASI HIPERTENSI DAN TERAPINYA Susanto, Yugo Alfian, Riza hypertension educational leaflet of hypertension and treatment behaviour blood pressure Kesehatan Masyarakat Hypertension is a condition of systolic blood pressure >140 mmHg and diastolic > 90 mmHg persistenly. Hypertension is as one of major risk factors for cardiovascular disease, kidney failure, and stroke. The prevalence of hypertension in South borneo is 30.8 %. The behavior is a key factor that inhibited blood pressure control that requires intervention to change patient behavior. The aim of this study were to investigate the influence of  pharmacists educational leaflet of hypertension and treatment given to behavior and blood pressure patient of ambulatory hypertension patients at Internal Disease Policlinic Dr. H. Moch Ansari Saleh Banjarmasin hospital. The study was conducted with quasi-experimental design. The ambulatory hypertension patients data were collected prospectively during the period of April until mei 2015. This study involved 45 patients who included in the inclusion and exclusion criteria. Data collection was conducted by to assess the level of the patient’s behavior questionnaires and the blood pressure data were taken from their medical record. The results showed that giving educational leaflet of hypertension and treatment could increased knowledge, attitude, and practice significantly (p<0,05). The average of knowledge and attitude scores in pre measurement 2,60 ± 0,71, 2,44 ± 0,65 increased in post measurement 2,95 ± 0,20, 2,77 ± 0,51 were statistically different p=0,00. The average of practice scores in pre measurement 2,15 ± 0,85 increased in post measurement 2,48 ± 0,75 were statistically different p=0,03. The systolic and diastolic blood pressure also decreased with an average reduction of 14,44 ± 9,18 mmHg for systolic and diastolic was 9,55 ± 10,21 mmHg. Over all it can be conculed that the giving educational leaflet of pharmacist can improve patient behavior. Furthermore, it can decrease the blood pressure (p<0,05).  Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/26 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung; 140-144 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 2 (2015): Jurnal Ilmiah Manuntung; 140-144 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/26/25 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/27 2021-01-31T08:14:11Z jim:ART

PERBANDINGAN PELARUT ETANOL DAN AIR PADA PEMBUATAN EKSTRAK UMBI BAWANG TIWAI (Eleutherine americana Merr) MENGGUNAKAN METODE MASERASI Sa'adah, Hayatus Nurhasnawati, Henny bawang tiwai maceration extract yields Farmakognosi Bawang tiwai (Eleutherine americana Merr) is one kind of medicinal plant. To obtain an active substances with good physical and chemical properties, it is needs to do optimization of making extracts, one with solvent optimization. Type of solvent will determine the types of extracted substances in accordance with the polarity. On this research, extraction of bawang tiwai bulbs simplicia by maceration method using ethanol and water as solvent. This research is an experimental research with varying ethanol and water in a three comparison solvent that is water, ethanol, and mixture of water-etanol, then the yields is calculated. Furthermore, the data were analyzed statistically using ANOVA program to determine significant differences in the three yields. In each extract was conducted phytochemical screening to determine the content of secondary metabolites. The results showed significant differences in the yield of bawang tiwai extract with three treatments and two repetitions. The results of average yields using water as solvent is 8.75%, ethanol 5.3%; and water-etanol 8.31% Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/27 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung; 149-153 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 2 (2015): Jurnal Ilmiah Manuntung; 149-153 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/27/26 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/28 2021-01-31T08:14:09Z jim:ART

ANALISIS KUANTITATIF KESADAHAN TOTAL AIR MINUM ISI ULANG YANG DIJUAL DI WILAYAH KAYU TANGI KOTA BANJARMASIN Musiam, Siska Darmiani, Siti Putra, Aditya Maulana Perdana total hardness refill drinking water complexometry Kesehatan Masyarakat Water is one of the important needs for human body. Therefore, water which consumed should be healthy and have certain quality. One of its quality parameter is total hardness. Total hardness is the hardness which caused by Ca2+ and Mg2+ ions. Hard water, or water with a high level of total hardness, if consumed in long term can lead to hyperparatyroidsm, Nephrolithiasis, and musculusweakness. The aim of this study were to determine total hardness level of refill drinking waterwhich sold in Kayutangi Banjarmasin and to compare it with the standard parameter of total hardness in Permenkes 492/Menkes/IV/2010 which is 500 mg/L in maximum. There were 16 samples in this study that taken from refill drinking water store were found accidentally. The quantitative analysis was done by complexometry titration method with Na2-EDTA as titrant and Eriochrome Black T as indicator. The results showed that the ranges of total hardness level of 16 samples that determined between 35,64 – 99,00 mg/L which is suitable with the standard based on Permenkes 492/Menkes/IV/2010 Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/28 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung; 145-148 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 2 (2015): Jurnal Ilmiah Manuntung; 145-148 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/28/27 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/29 2021-01-31T08:14:16Z jim:ART

ISOLASI DAN IDENTIFIKASI BAKTERI ASAM LAKTAT (BAL) DARI BUAH MANGGA (Mangifera indica L.) Ibrahim, Arsyik Fridayanti, Aditya Delvia, Fila Mangifera indica L. lactic acid bacteria spoiled isolation Kimia The research has been done for the isolation and identification of lactic acid bacteria (LAB) from mango (Mangifera indica L.). This research aimed to isolated of lactic acid bacteria that is in mango (Mangifera indica L.) and determine the characteristics of lactic acid bacteria isolate (LAB) of mango (Mangifera indica L.). The method used is spoiled  technique of mango (Mangifera indica L.) and isolation using selective media MRS Broth and MRS Agar. The identification isolate of lactic acid bacteria (LAB) used methods macroscopically and microscopically with indirect coloring, gram staining and used biochemical with katalase testing. The results obtained in the form of characteristic isolate of lactic acid bacteria displayed form of bacteria with circle, smooth surface, curve, entire side and white. The microscopically displayed stick form of bacteria and purple with gram coloring Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/29 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung; 159-163 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 2 (2015): Jurnal Ilmiah Manuntung; 159-163 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/29/28 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/30 2021-01-31T08:14:19Z jim:ART

DOSIS OPTIMUM BIJI KELOR (Moringa seed) DALAM MENURUNKAN KEKERUHAN (Turbidity) AIR SUNGAI BETAPUS DI KELURAHAN SEMPAJA UTARA KOTA SAMARINDA Wahyuni, Marjan Optimum dose moringa seed turbidity Farmakognosi Water is used as daily necessities which must meet the standards of raw water for drinking water, household, and other – other. As in the waters of the North Sempaja Betapus Sub District of North Samarinda territory that location is dihulu Karangmumus River. Physically the water is cloudy, colored and contains organic / inorganic. The aim of this study was to determine the optimum dose of moringa seed in reducing turbidity (Turbidity) Water Betapus River in the Village of North Sempaja Samarinda.This research is a quasi-experimental (Quasi Experiment) or the design of a series of time (Time Series Design) which make measurements before and after affixing moringa seeds with sampling methods Grab Sample for 1 day. This experiment uses a method to purify raw water Jartest Betapus River by adding powdered moringa seeds (Moringan oleifera) into 1 liter of water by varying the dose of 0.5 g / L, 1.0 g / L, 1.5 g / L, and 2.0 g / L. Results of research conducted on Betapus River water showed that the level of turbidity (Turbidity) amounted to 79.1 NTU with a pH of 6.8, so it is said to be ineligible clean water turbidity according Permenkes RI 416 / Menkes / Per / IX / 1990, namely that allowed 25 NTU. After affixing moringa seeds with a variety of different doses, the results showed as follows: the dose of 0.5 g / L = 4.52 NTU; a dose of 1.0 g / L = 7.76 NTU; dose of 1.5 g / L = 9.14 NTU, and a dose of 2.0 g / L = 8.51 NTU. The optimum dose range moringa seeds needed at River raw water Betapus = 0.5 g / L with a percentage of 94.28%. For people who use the river water as the need for clean water for toilets (Bath Wash Case) and so on, you should do a simple treatment with Moringa seed powder according affixing the optimum dose prescribed to reduce levels of turbidity (Turbidity) in water. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/30 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung; 164-167 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 2 (2015): Jurnal Ilmiah Manuntung; 164-167 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/30/29 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/31 2021-01-31T08:14:21Z jim:ART

FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN DIARE PADA BALITA DI KELURAHAN KAMPUNG BUGIS KOTA TANJUNGPINANG TAHUN 2014 Pusparianda, Dewi diarrhea clean water hand washing toilet food sanitation hygiene Kesehatan Masyarakat Health problems greatly influenced by behavioral factors and environmental factors. One of the diseases based on an unhealthy environment is diarrhea. Environmental sanitation and personal hygiene are less healthy will facilitate contracting the disease agents that cause diarrhea. This study aims to identify factors associated with the incidence of diarrhea in infants in Kampung Bugis Tanjungpinang 2014. Type of analytical research and observational methods Case control study design. Study subjects were sampled of 46, (23 cases and 23 controls). Sampling was conducted by consecutive sampling. Statsistik analysis using chi square test.  The results showed 67.4% use clean water that meets the requirements; 58.7%, had the habit of washing hands; 67.4% of healthy latrine use and 65.2% who do hygiene sanitation food properly. Results of statistical test Chi-Square on bivariate analysis showed no relationship fresh water use (p = 0.000); handwashing (p = 0.000); healthy latrine (p = 0.011) and food sanitation hygiene (p = 0.005) and the incidence of diarrhea. From the above results, it is necessary to motivate the community outreach effort in the procurement and use of clean water that meets the requirements, good hand washing habits, and the use of latrines are eligible. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/31 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung; 168-171 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 2 (2015): Jurnal Ilmiah Manuntung; 168-171 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/31/30 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/32 2021-01-31T08:14:24Z jim:ART

FAKTOR SOSIODEMOGRAFI DENGAN KELANGSUNGAN HIDUP BAYI DI INDONESIA (ANALISIS DATA SDKI 2007) Dewi, Utami infant’s survival sociodemography infant Kesehatan Masyarakat It is recommended for a mother to initiate to give early breastfeeding for a newborn as the first breast milk is known to be nutritious and contains antibody. The delay of breastfeeding shows that non breast milk-supplementary food is given. Based on BPS and Macro International data 65% of infants received pre-lacteal feeds besides breast milk in their three days of life.The known relationship between sociodemography and infants’ survival in Indonesia.This was an observational study with a cohort retrospective study design by using IDHS data year 2007. Samples were all infants (<12 months, breastfed after birth) from mothers aged 15-49 years old as many as 15.679 mothers. The independent variable was sociodemography and the dependent variable was infants’ survival. The analyses used univariable, bivariable, and survival analysis with Kaplan-Meier and Log regression. Bivariable analysis using survival Kaplan-Meier showed that there was significant relationship between mother age with Log Rank 15,89 and p<0,05, mother education with Log Rank 16,25 and p<0,05 , place of residence with Log Rank 18,84 and p<0,05, socioeconomic with Log Rank 38,71 and p<0,05, birth attendant with Log Rank 17,35 and p<0,05 and infants’ survival. Sociodemography  was associated significant with an infant survival. Other factors affecting infant’s survival were birth attending with no professional and mother’s age <20 and ≥35 years old. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/32 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung; 172-180 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 2 (2015): Jurnal Ilmiah Manuntung; 172-180 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/32/31 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/33 2021-01-31T08:14:28Z jim:ART

UJI AKTIVITAS EKSTRAK ETANOL 96% BIJI SRIKAYA (Annona squamosa L.) SEBAGAI ANTIDIARE YANG DISEBABKAN OLEH BAKTERI Shigella dysenteriae DENGAN METODE DIFUSI CAKRAM Rianto, Leonov Handayani, Indri Astuti Septiyani, Annisa Custard apples seed (Annona squamosa L) antidiare Shigella dysenteriae disc diffusion method Farmakognosi This research aims to find out how to extract ethanol 96% seed custard apples as Antidiarrhoeal that is caused by bacteria Shigella dysenteriae with different concentrations and compare with chloramphenicol. In addition, also to find out whether their respective inhibitory power of concentration of ethanol 96% seed extract custard apples have a difference in meaning. Research done by experimental methods, was carried out in the laboratory of pharmaceutical Academy IKIFA. Testing was done using the diffusion disc method. The concentration of ethanol 96% seed extract custard apples are used i.e. 15%, 30%, 45%, 60%, and 75%. As positive controls used chloramphenicol 30 µg/ml and NaCl 0.9% as the negative control. Each test is carried out as many as eight repetitions. The results showed an average diameter drag power which formed on the test solution with a concentration of 15%, 30%, 45%, 60% and 75% respectively of 6,887 mm, 11,49 mm, 8,144 mm, 7,694 mm, 7,150 mm, whereas for chloramphenicol for 40,31 mm. Based on the results of the statistical tests there are meaningful differences between concentrations showed a meaningful difference between the concentration of 15% and 30%, 15% and 60% and 15% and 75%. Conclusion of this research is at a concentration of 15%, 96% ethanol extract of seeds of custard apples have been able to inhibit the growth of bacteria, Shigella dysenteriae Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/33 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung; 181-186 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 2 (2015): Jurnal Ilmiah Manuntung; 181-186 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/33/32 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/34 2021-01-31T08:14:29Z jim:ART

UJI EFEKTIVITAS ANTHELMINTIK EKSTRAK RIMPANG BANGLE (Zingiber purpureum Roxb.) TERHADAP CACING Ascaridia galli SECARA IN VITRO Susanti, Yanthi Astuti, Indri Astuti, Ade Ari Dwi Zingiber purpureum Roxb. Ascaridia galli anthelmintic pirantel pamoat Farmakognosi The research was conducted to observe anthelmintic efficacy on rhizome extract bangle against Ascaridia galli by in vitro procedure. Experimental study was conducted, with samples rhizomes bangle powder and  maceration method in three concentrations of 2%, 4% and 8%. The experimental animals used is Ascaridia galli with NaCl 0.9% as negative control and a pyrantel pamoate suspension as positive control with concentrations of 0.2%, 0.4% and 0.6%. The study was conducted in July 2014 at the Laboratory on IKIFA Academy of Pharmacy. The data analysis used is a probit analysis. Results of Research was rhizome extract bangle (Zingiber purpureum Roxb.) having as anthelmintic efficacy against Ascaridia galli with LC50 2.29% and LT50 in 4 hours 3 minutes 18 seconds Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/34 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung; 187-192 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 2 (2015): Jurnal Ilmiah Manuntung; 187-192 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/34/33 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/35 2021-01-31T08:14:32Z jim:ART

GAMBARAN INTERAKSI OBAT HIPOGLIKEMIK ORAL (OHO) DENGAN OBAT LAIN PADA PASIEN DIABETES MELITUS (DM) TIPE II DI APOTEK IMPHI PERIODE OKTOBER 2014 SAMPAI MARET 2015 Meryta, Aries Efrilia, Mega Chandra, Pra Panca Bayu drug interaction oral hypoglycemic drug type II of diabetes mellitus (DM) Farmakologi Increasing complications of diabetes mellitus (DM) have tendency to amount of drug use, which can increase the risk of drug interaction. Drug interaction is a situation arising of administrations more than one drug at the same time that effects each drug can be interfere each other and or both are mutually and or undesirable side effect may a rise which could potentially harm and or doesn’t give clinically significant effect. This research aims to determinate the potential interactions and mechanisms of drug interactions and impacts based on the severity of the effect of therapy in patients type II of diabetes mellitus (DM) at Imphi’s Pharmacy in the period October 2014 until March 2015. The research used descriptive evaluative and retrospective method based on recipe sheets. Data analysis have done by screening of drug interaction and using drug interaction from software lexicomp and drug interaction stockley. The results showed that there are 28 recipe sheets (16,37%) from 171 recipe sheets of 110 patients that potentially occur pharmacodynamic mechanism of drug interaction with as many as 36 events (64,29%) as well as the mechanisms of drug interaction based on the severity of the effect of moderate kind of therapy as much as 40 events Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/35 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung; 193-199 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 2 (2015): Jurnal Ilmiah Manuntung; 193-199 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/35/34 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/36 2021-01-31T08:14:35Z jim:ART

KELENGKAPAN INFORMASI MENGENAI CARA PENGGUNAAN PEAK FLOW METER YANG DIBERIKAN KEPADA PASIEN ASMA DI APOTEK Lorensia, Amelia Queljoe, Doddy De Santosa, Kristian Abram information on how to use peak flow meter asthma pharmacy Layanan Kesehatan Measurement of lung fungction  is a way to determine the effectiveness of a given therapy. A monitoring asthma symptoms is to see the value of peak expiratory flow (PEF) with a peak flow meter. The measurement is objective and can be used to predict the prognosis of asthma through the monitoring of conditions of the lung. This study aims to find out information on the use of a peak flow meter explanations given to the patient’s pharmacist in a pharmacy in a town in East Java. This research method is a non-experimental with cross sectional study. This study uses observation techniques in the form of a checklist, using the concept of a mysterious patient. Sampling by the proportional method, and then the data will be processed descriptively. The research sample of 80 pharmaceutical personnel consisting of 33 pharmacists and 47 non-pharmacists. In the group of non-pharmacists and pharmacists, the points most overlooked is the explanation of the recording of the results (number 6) and compared with the best value (number 8). Pharmacists still need to improve in understanding the basics and techniques in order to use a peak flow meter can help asthma patients to monitor their asthma medication Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/36 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung; 200-206 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 2 (2015): Jurnal Ilmiah Manuntung; 200-206 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/36/35 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/37 2021-01-31T08:14:14Z jim:ART

FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN GANGGUAN FUNGSI PARU PADA PEKERJA PEMBUAT KASUR (STUDI KASUS DI DESA BANJARKERTA KARANGANYAR PURBALINGGA) Yuliawati, Ratna Pulmonary dysfunction matttres maker dust inhalation Kesehatan Masyarakat Mattress maker is one of the high-risk job of lung function. Dust from the production of an effect on lung function. Research describe dust from production assosiated to the pulmonary dysfunction. Previous studies explain the illness rate reached 70% in workers who inhale cotton dust. Describe the various factors assosiated to the pulmonary dysfunction  between age, nutritional status, years of service, the use of masks, ventilation, workplace ownership, and the amount of dust inhaled by the incidence of lung function, job characteristics, and the amount of dust inhaled by the mattress makers in the District Karanganyar Purbalingga. This study was an cross-sectional, with a total sample of 80 workers mattress maker. The independent variable in this study is a age, nutritional status, years of service, the use of masks, ventilation, workplace ownership, and levels of total particles inhaled. The analysis was performed using univariate, bivariate and multivariate as well as by calculating the ratio of prevalence. The results showed that there are 4 variables significantly associated with lung function. that workers exposed to dust> 0.2 mg/m3 per day with a ratio of 27.203 prevalent (95% CI = 1.885 to 39,257) Working period (≥ 10 years), with a ratio of 21,502 prevalent (95% CI = 9.559 to 483,65) The use of masks (not always use) with the ratio of 43.965 prevalent (95% CI = 2.831 to 682,80) Ownership separate workplaces with 27.583 prevalent ratio (95% CI = 1.955 to 389,25). The risk factors significantly associated with impaired lung function is inhaled dust particles, years of service, the use of masks and a separate work between sections. suggested to the labor department and the health department to conduct promotive and preventive so that workers can be maintained mattress maker of health and safety work Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/37 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung; 154-158 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 1 No. 2 (2015): Jurnal Ilmiah Manuntung; 154-158 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/37/36 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/38 2021-01-31T08:05:48Z jim:ART

UJI EFEKTIVITAS DAYA ANTHELMINTIK JUS BIJI MENTIMUN (Cucumis Sativum, L) TERHADAP CACING ASCARIDIA GALLI SECARA IN VITRO Rianto, Leonov Astuti, Indri Prihatiningrum, Ika anthelmintic Cucumis sativum L Ascaridia galli pirantel pamoat Farmakognosi Research has been conducted to review the efficacy of anthelmintic on seeing the juice of cucumber seeds ( Cucumis sativum , L ) Against Ascaridia galli by in vitro method . By experimental study was conducted , with samples of seeds of cucumber ( Cucumis sativum , L ) The smoothed and made with 3 concentrations That is 15 % , 30 % and 60 % . The experimental animals used is Ascaridia galli with negative control solution of NaCl 0.9 % and a positive control pyrantel pamoate suspension with concentrations of 0.2 % , 0.4 % and 0.6 % . The analysis of data is probit analysis be adopted . Results Of Research was claimed that the juice of cucumber seeds ( Cucumis sativum , L ) have anthelmintic efficacy against Ascaridia galli with 12.76 % LC50 and LT50 3 hours 4 minutes 39 seconds . Comparising with tables of LD50 value, the obtained dose is 472,59mg / kg and it is in no toxic category. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/38 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 1-7 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 1 (2016): Jurnal Ilmiah Manuntung; 1-7 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/38/37 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/39 2021-01-31T08:06:04Z jim:ART

PERBEDAAN PENGETAHUAN DAN SIKAP PASIEN DIABETES MELLITUS RAWAT INAP RUMAH SAKIT ISLAM SAMARINDA SEBELUM DAN SESUDAH KONSELING GIZI DENGAN MENGGUNAKAN MEDIA AUDIOVISUAL Siswanto, Siswanto Kamba, Ismail Aminah, Siti Nutrition counseling audiovisual media Knowledge attitude DM Kesehatan Masyarakat Diabetes mellitus is one of the communicable diseases that have become a public health problem, not only in Indonesia but also the world. Currently morbidity of diabetes mellitus is increasing every year, where in 2006 there were 14 million people in 2011 and ranks fourth with 773 cases. DM is also a cause of disease mortality by 5.8%. And Samarinda own particular Islamic Hospital years 2009, there were 449 patients with DM, and 2011 an increase in the 1931 patients with diabetes mellitus. To increase patients’ knowledge about diabetes and diabetic patients be directing attitudes that support or positive attitude towards keeping blood glucose levels to remain normal. Methode to use pra eksperiment with one group pretest posttest. individual conseling withAudiovisual media. There is increased knowledge about diabetes diabetic patients before and after intervention with increasing value of 3.77 (p value = 0.000) and increase in attitudes regarding diabetes mellitus diabetic patients with an increase in the value of 5,35 (p value = 0.003). There was an increase in knowledge and attitudes of patients hospitalized with diabetes mellitus hospital after islam samarinda given nutritional counseling using audio-visual media Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/39 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 8-14 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 1 (2016): Jurnal Ilmiah Manuntung; 8-14 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/39/38 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/40 2021-01-31T08:06:23Z jim:ART

ANALISIS TINGKAT PELAYANAN PASIEN POLIKLINIK RUMAH SAKIT ABDUL RIVAI DI KABUPATEN BERAU Dasia, Maya Abdul Rivai hospital service quality patient satisfactory Layanan Kesehatan The aim of the study was to determine the quality of service provided by Abdul Rivai hospital in District Berau. The benefit of the research is as an input for Abdul Rival hospital to maintain the quality of service. In this study, the assessment of service quality is divided into five categories: Manners of employees, employee communication ability, speed of service, hospital facilities, and employee performance. All categories show that consumer’s perception of services provided by hospital has been quite satisfactory. The calculation of average weighted values for the five categories used are manners of employees, employee communication ability, speed of service, hospital facilities, and employee performance are 3,126 Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/40 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 15-21 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 1 (2016): Jurnal Ilmiah Manuntung; 15-21 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/40/39 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/41 2021-01-31T08:06:49Z jim:ART

PENGARUH LAMA PEREBUSAN SIMPLISIA DAUN APAH (Albertisia papuana Becc.) YANG DIGUNAKAN SEBAGAI PENYEDAP MAKANAN OLEH MASYARAKAT KAB. TANA TIDUNG TERHADAP ANGKA CEMARAN MIKROBA Rosnah, Rosnah Hendra, Medi Kusumawati, Eko Apah’s Leaves (Albertisia papuana Becc.) Infusion Simplisia Microbial Contamination Numbers Farmakognosi The purpose of this study is to determine the effect of long simplicia Apah’s leaves (Albertisia papuana Becc.) that’s used as a food’s flavoring by people of Kab. Tana Tidung against microbial contamination numbers. The design of research used a pattern completely randomized design (RAL), with a dilution series of samples 10-8, 10-9 and 10-10 and different boiling’s level (5, 10, 15, 20 and 25 minutes). The results obtained that the longer of boiling process is used, then the less the number of microbial contamination of colony growth. Average number of microbial contamination in samples in the boiling of 5 minutes is 92 x 1010 microbial colonies, in boiling 10 minutes is 87 x 1010 microbial colonies, in boiling 15 minutes is 56 x 1010 microbial colonies, in boiling 20 min is 44 x 1010 colonies of microbes and the boiling simplicia infuse for 25 minutes is 33 x 1010 colonies of microbes. Based of Analysis variance variety in each treatment showed that in boiling 20 minutes and 25 minutes showed real significant difference (p <0.05), but the boiling 5, 10 and 15 minutes there was no significant difference (P> 0.05). The results of the Anova, showed that in boiling treatment of simplicia Apah’s leaves (Albertisia papuana Becc.) significantly affects the growth of microbial colonies. Analysis of Least Significant Difference (LSD) at the level of 95%, the result that the effects of long boiling the simplicia Apah’s leaves (Albertisia papuana Becc.) which is used as a food flavoring by people of Kab. Tana Tidung, significant effect on the numbers of microbial contamination Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/41 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 22-27 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 1 (2016): Jurnal Ilmiah Manuntung; 22-27 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/41/40 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/42 2021-01-31T08:07:05Z jim:ART

UJI PENDAHULUAN DAUN TENEM Litsea cubeba (Lour.) Pers Supriningrum, Risa Hendra, Medi Misak, Hendri Litsea cubeba (Lour)Pers organoleptic macroscopic microscopic class of chemical compounds Farmakognosi Litsea cubeba (Lour Pers.) has been used by the Dayak community Lundayeh and Kenyah, the village of Long Berang, District Mentarang, North Borneo, as drug . Leaves and bark used as medicine for diarrhea. Preliminary data concerning the characteristics and content of secondary metabolites has not been reported. This study aims to determine the organoleptic, macroscopic,  microscopic characteristics and content of secondary metabolites tenem leaves. The results showed that the leaf tenem have organoleptic characteristics typical aromatic smell like citrus (lemon), taste slightly bitter, slightly spicy, chelates. Macroscopic characteristics in the form of a single leaf, lanceolate, elongated, tapered leaf tip, leaf base tapering, bone pinnate leaves, upper surface shiny, lower surface dull and slightly hairy, color light green to dark green. Microscopy test results showed fragments of sklereid, oil cell, stomata type of parasitic, non-glandular trichomes. Simplicia tenem leaf powder contains alkaloids, tannins and terpenoids. The ethanol extract of leaves tenem containing compounds, terpenoids, tannins, alkaloids Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/42 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 28-31 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 1 (2016): Jurnal Ilmiah Manuntung; 28-31 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/42/pdf Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/43 2021-01-31T08:07:22Z jim:ART

PENGARUH KEMASAN TERHADAP AKTIVITAS ANTI BAKTERI SUSPENSI ERITROMISIN SETELAH PENYINARAN DENGAN SINAR MATAHARI LANGSUNG Hidayati, Nurul Erythromycin Staphylococcus aureus ATCC 25923 hydrolysis dry syrup suspension photolysis package expose Kimia Erythromycin is a type of antibiotic medication. The drug is unstable when in the water because it can undergo hydrolysis process. Fortunately, it can be prevented by making dry syrup dosage form. In addition to hydrolysis, erythromycin can also have photolysis. For preventing the reaction, it can be done by packing the medication in an opaque and tightly closed container. This research was conducted to determine the effect of packaging on the stability of erythromycin suspension that has been exposed to direct sunlight within a period. The research was done by exposing erythromycin suspension, which was packed with three kinds of color packaging namely brown, translucent, and opaque, for 30 minutes, 60 minutes, 90 minutes and 120 minutes, then continued by a microbiological test with a diffusion method to determine the activity of erythromycin against Staphylococcus Aureus. The results of the research showed the existence of diameter of barrier areas around the spots that were given a test solution. It means that the test solution has antibiotic activity against bacteria. Preparations packaged in brown color have higher inhibition when compared with the opaque and translucent. It shows that the erythromycin suspension packaged in brown colors was more efficient in stabilizing the preparation Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/43 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 32-38 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 1 (2016): Jurnal Ilmiah Manuntung; 32-38 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/43/41 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/44 2021-01-31T08:07:42Z jim:ART

ANALISA LOGAM BESI (Fe) DI SUNGAI PASAR DAERAH BELANGWETAN KLATEN DENGAN METODE SPEKTROFOTOMETRI SERAPAN ATOM Nurhaini, Rahmi Affandi, Arief iron (Fe) Atomic Absorption Spectrophotometer River Kimia Iron (Fe) is one of many heavy metals that is corrosive resistant, dense, and has a low melting point. If accumulated in the body, the metal can cause some medical conditions, such as irritation to skin and eyes, breathing problems, and in the long term, cancer. This research aims to know generally the spread of metallic iron (Fe) in the river Pasar in Belangwetan, Klaten. This study was conducted using an observational method in which researchers did not examine the effects of interventions. Sampling was done using purposive sampling method taken from three points, namely the upper, middle, lower. Determination of iron levels by Atomic Absorption Spectrophotometer (AAS) obtained a positive result, and the data was processed using SPSS to determine the Mean and Standard Deviation. Of the research result, it could be known the Mean score was 2.33 ppm and SD was 0.0352. The result of this research indicated that the levels of iron in the river Pasar in Belangwetan were 2.33 ppm. It means that the levels violate the regulation of the Minister of Health of the Republic of Indonesia, which is not more than 1mg/L (1ppm) in the clean water Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/44 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 39-43 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 1 (2016): Jurnal Ilmiah Manuntung; 39-43 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/44/42 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/45 2021-01-31T08:08:00Z jim:ART

PENGARUH PROSES PEREBUSAN TERHADAP KADAR PROTEIN YANG TERKANDUNG DALAM TAUGE BIJI KACANG HIJAU (Phaseolus Radiatus) Agustina, Anita Rahmawati, Desi Protein Mung Bean Sprouts Lowry Method Farmakognosi Protein is an important or main component of animal and human cells. The source of vegetable protein can be obtained from soybeans and other legumes, as well as their processed results. This component can be denatured due to changes in temperature, pH, heavy metal ions, mechanical movement, alcohol, acetone, ether, and detergent. The main aim of this study was to determine the effect of boiling on protein in the seeds of mung beans. The samples were analyzed using the Lowry method. The result of quantitative test showed that the average level of protein in the samples before boiled was 1.664% w/w, while after boiled was 0632% w/w. The statistical test showed that t-score of the sample was 43.827 and t-table was 2.920, and p-score was 0.001. Of the results of the study, it can be concluded that there is a significantly difference between the levels of protein before and after boiled. Boiling gives effect to the protein levels in the samples. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/45 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 44-50 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 1 (2016): Jurnal Ilmiah Manuntung; 44-50 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/45/43 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/46 2021-01-31T08:08:15Z jim:ART

FORMULASI SEDIAAN SABUN MANDI PADAT DARI EKSTRAK BUAH APEL (Malus domesticus) SEBAGAI SABUN KECANTIKAN KULIT Chan, Adek Apples Solid Bath Soap As The Beauty Soap Of The Skin Farmakognosi As the development time of usage and utilization of traditional medicine in Indonesia is experiencing a very rapid progress. Interest of the community to utilize natural materials back to health is greatly improved. Apple or (pyrusmalus) is one among the faforit fruit in the family rosaceae or rose-mawaran. Apple plants allegedly came from around israel-Palestine, then spread throughout the world, including indonesia. Europe and Australia is the country’s most used to develop crop of apples in agribusiness. Apples contain a natural anti oxidant which is great for the health of the skin and eyes. This research uses research methods laboratory ekperimental Soap to be created with a penembahan extract of apples made with olive oil. Apple fruit is extracted by means of maceration using penyari ethanol. Ethanol extract of Apple made in the form of solid bath soaps and bath soaps performed the examination test includes solid Favorites, pH, testing methods and solid bath Soap Irritation Test made with a concentration of 2.5%, 3.5%, 4.5%. The results of the test checks gladness solid bath Soap preparations obtained are really like 13 people, like 4 people, 3 people and less like don’t like 0, pH 8.3-7.3, on the test of irritation in the preparations of solid bath SOAP from Apple fruit extracts do not cause skin redness and itching. The conclusion of the researchers extract of apples (Malusdomsticus) can be formulated in the form of preparation of solid bath Soap. The advice of researchers is expected for the next researcher to be able to formulate the Apple fruit extract (Malusdomesticus) in the form of other preparations, such as face masks. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/46 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 51-55 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 1 (2016): Jurnal Ilmiah Manuntung; 51-55 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/46/44 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/47 2021-01-31T08:09:36Z jim:ART

HUBUNGAN PEMBERIAN SUPLEMEN ZAT BESI (FE) PADA IBU HAMIL DENGAN BERAT BADAN LAHIR RENDAH (BBLR) DI RSUD ABDUL WAHAB SJAHRANIE SAMARINDA K, Iriyani low birth weight Fe Supplements Farmakologi Babies of low birth weight is a baby who weighed less than 2500 grams. Low birth weight is caused by several factors i.e. a premature birth, small size baby, and IUGR (intra-uterine growth retardation). The purpose of this study was to determine the correlation between supplemental iron (Fe) in pregnant women and low birth weight. The design research is quantitative method with Case Control approach using 116 samples from 58 cases and 58 control groups with a ratio of 1:1 for both sexes. The sampling method is purposive Sampling. Dana analyzed using Chi Square correlation test with CI 95% at value of α of 5%. The results showed that there was a correlations between supplemental Fe in pregnant women (ρ value = 0,001 with OR = 8.25) with low birth weight.  To reduce the high incidence of low birth weight, pregnant women are suggested to take Fe supplements or taking high content Fe meal everyday. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/47 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 56-59 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 1 (2016): Jurnal Ilmiah Manuntung; 56-59 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/47/45 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/48 2021-01-31T08:09:42Z jim:ART

ANALISIS KUALITATIF FORMALIN PADA TAHU MENTAH YANG DIJUAL DI PASAR KALINDO, TELUK TIRAM DAN TELAWANG BANJARMASIN Ariani, Novia Safutri, Maida Musiam, Siska Qualitative analysis formaldehyde crude tofu conventional Kimia Tofu is one of favourite food in Indonesia because it is containing the nutrients which body needs, such as protein. Tofu comes from processed soybeans and contains high water, so it can only save for 1 or 2 days in storage. Because of that reason several   manufacturers or dealers add additional ingredients, one of them was formaldehyde to made tofu were durable to be restored and increases consumer appeal. The aim of the study was to identifity the contain of formaldehyde at crude tofu in Kalindo, Teluk Tiram and Telawang market Banjarmasin. The investigated sample was white crude tofu were 19 samples obtained with accidental sampling. The type of research was descriptive research. Qualitative analysis of formaldehyde at crude tofu was done with conventional method by using Ag(NH3)2NO3 and KMnO4 0,1N reagents. The result of study shows that crude tofu was sold in Kalindo market 90% (9 of 10 samples) positive contain formaldehyde, 100% (4 of 4 samples) at Teluk Tiram market positive contain formaldehyde and 80% (4 of 5 samples) at Telawang market positive contain formaldehyde Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/48 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 60-64 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 1 (2016): Jurnal Ilmiah Manuntung; 60-64 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/48/46 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/49 2021-01-31T08:09:44Z jim:ART

UJI KUALITAS SERUM SIMPANAN TERHADAP KADAR KOLESTEROL DALAM DARAH DI POLTEKKES KEMENKES KALTIM Hartini, Supri Suryani, Maria Eka Serum Storage time Cholesterol Farmakologi Clinical Chemistry Examination Guidelines stated several factors may affecting the stability of the specimen i.e. contaminant germs and chemicals, exposure to sunlight, the effects of temperature and metabolism of living cells such as blood cells. Blood specimens should be stored in the form of serum in a refrigerator at a temperature of 2-80 C. This study aimed to compare cholesterol levels of serum with no erythrocyte and with erythrocytes during storage for 3 and 9 days at 2-8ºC. This is an analytical survey to compare cholesterol levels in serum blood during storage. Data was analyzed using Independent Sample t-test. The result showed value p (0.410) is greater than α (0.05), so there is no correlation between serum with erythrocytes and with no erythrocytes in cholesterol at a temperature of 2-8 0C stored for 3 days and the p-value (0.162) is greater than α (0.05) then pat concluded that there was no influence of serum with erythrocytes and without erythrocytes to changes in cholesterol at a temperature of 2-8 0C during storage of 9 days Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/49 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 65-69 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 1 (2016): Jurnal Ilmiah Manuntung; 65-69 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/49/47 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/50 2021-01-31T08:09:46Z jim:ART

ANALISIS KINETIKA PELEPASAN TEOFILIN DARI GRANUL MATRIKS KITOSAN Suprianto, Suprianto release kinetics theophylline and chitosan Kimia Moment the drug dosage form development, it is important to study the drug release or dissolution that is recognized as an element in drug development. Mathematical models could help optimize the design of drugs to produce models of drug release information. Analysis of quantitative values obtained when depicting dissolution drug release profiles more easily when the mathematical concepts used to describe the drug release kinetics model. Model release of drugs known include zero order, first order, Higuchi models, models Hixon Crowell and Peppas Korsmeyer models. The purpose of this review apply mathematical concepts to study the phenomenon of drug release theophylline granules matrix made from chitosan Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/50 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 70-80 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 1 (2016): Jurnal Ilmiah Manuntung; 70-80 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/50/48 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/51 2021-01-31T08:09:48Z jim:ART

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL LIMBAH KULIT BUAH APEL (Malus domestica Borkh.) TERHADAP RADIKAL BEBAS DPPH (2,2-Diphenyl-1-Picrylhydrazil) Pertiwi, Ratih Dyah Yari, Cut Ervinar Putra, Nanda Franata Antioxidant Activity Apple Peel Waste DPPH Farmakognosi Recently, many plants have not been utilized properly, one of those is apple plant. There are several types of apples which are widely consumed and used as processed products, among others, as candied apples, syrup and fruit juice. The effluent from the process in the form of processed peel and pulp is not only used as a substitute for animal feed and fertilizer plants, but also used as a natural antioxidant that is needed by the human body against various free radical. Most of the people who like to consume apples prefer to discard the apple peel without using it. Apple peel contains quercetin substances, which needed to increase the levels of antioxidants. The preparation of ethanol extract from apple peels waste is used by maceration method using solvent 70% ethanol. To test the antioxidant activity towards free radical DPPH the extract was made into several concentrations, namely 10 ppm, 20 ppm, 30 ppm, 40 ppm and 60 ppm, and than mixed with a solution of DPPH with concentration of 100 ppm. The absorbance was measured using  a  spectrophotometer  UV-Visible.  Based  on  the  result  of  the  research,  the percentage  of  reduction  obtain  from  those  of  extract  concentrations  were  8.580%, 14.510%, 21.653%, 26.685% and 34,232%. From percentage reduction result, it was obtain IC50 in the amount of 87.795 ppm. Based on the IC50 values can be conclud that the ethanol extract of apple peel waste has strong antioxidant activity classification Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/51 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 81-92 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 1 (2016): Jurnal Ilmiah Manuntung; 81-92 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/51/49 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/52 2021-01-31T08:09:50Z jim:ART

PEMANFAATAN EKSTRAK HERBAL TERHADAP PRODUKTIVITAS DAN MUTU AYAM PEDAGING SEBAGAI UPAYA KETAHANAN PANGAN DI KALIMANTAN TIMUR BERBASIS PETERNAKAN RAMAH LINGKUNGAN Supomo, Supomo Siswanto, Eka Ventyrina, Ine Eleutherine americana L Andrographis paniculata ( Burm.f. ) Nees Cucurma xanthorriza Roxb Quality Broiler Medicinal plants Indonesia Farmakognosi Quality broilers become a serious problem for farmers. Many studies done to solve these problems, one of them by making use of natural materials. Some plants are known to have the ability to improve the quality of broilers as bitter, ginger and onions tiwai. This study aimed to determine the effect of ethanol extract of the herb on the quality of broilers. Subjects used is Strain Cobb broiler DOC. A total of 60 chickens were kept in a cage stage measuring 1.5 x 1.5 m for 30 days. Subjects were divided into five treatment where each treatment consisted of four tails. The experiment was conducted with three replications using a completely randomized design. Such treatment includes control (P0), the ethanol extract of sambiloto 0.02 % (P1), the ethanol extract of umbi bawang dayak 0.05 % (P2), the ethanol extract of temulawak 0,075 (P3), Product Imugas (P4). Quality parameters include coarse fat content and crude protein. The data obtained were statistically analyzed using analysis of variance (ANOVA). The results showed that the treatment of all types of ethanol extract of the herb can improve the quality of broilers compared to control (sig < 0.05), the type of treatment is best to P4. Quality parameters which include : crude protein and crude lipid. Levels of the protein, which is the highest in treatment P4 by 23.87% . Fat content, which is the lowest in treatment P4 of 10.50% Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/52 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 93-98 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 1 (2016): Jurnal Ilmiah Manuntung; 93-98 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/52/50 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/53 2021-01-31T08:09:53Z jim:ART

FORMULASI EKSTRAK ETANOL GAMBIR (Uncaria gambir Roxb.) DALAM BEDAK ANTI JERAWAT Warnida, Husnul Masliyana, Agustiani Sapri, Sapri Gambir (Uncaria gambir Roxb.) loose powder diffusion method Staphylococcus epidermidis Farmakognosi Acne occurs due to blockage of pilosebaseus (oil glands) and inflammation causing by Propionibacterium acne, Staphylococcus epidermidis and Staphylococcus aureus. The purpose of the study was to test the antibacterial activity of gambir (Uncaria gambier Roxb.) ethanol extract toward Staphylococcus epidermidis and to formulate gambir ethanol extract into a loose powder dosage form that meets the standards of physical powder quality. Gambir was macerated with 95% ethanol. Activity of gambir ethanol extract against Staphylococcus epidermidis was tested by diffusion method using varying concentrations 3%, 6% and 9% of gambir etanol extract. Afterward, gambir ethanol extract formulated into powder. Analyze of powder physical properties including organoleptic test, homogeneity and particle size distribution. The results showed gambirethanol extract 3%, 6%, 9% has inhibition zone diameter 3.6 mm, 4.2 mm, and 6.8 mm respectively. Gambir ethanol extract powder has a homogeneous, fine size with a light brown color and a distinctive gambir aroma. The average particle size of the powder is 236.17 μm Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/53 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 99-106 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 1 (2016): Jurnal Ilmiah Manuntung; 99-106 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/53/51 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/54 2021-01-31T08:09:57Z jim:ART

INVENTARISASI DAN IDENTIFIKASI TUMBUHAN OBAT SUB ETNIS KUTAI DESA GENTING TANAH KECAMATAN KEMBANG JANGGUT KABUPATEN KUTAI KARTANEGARA KALIMANTAN TIMUR Apriliana, Anita Hendra, Medi Sapitri, Atila Inventory And Identification Drug Plant Sub Etnic Kutai Farmakognosi Indonesia has rich tropical forests will be diverse plants that can be used as a traditional medicine, ranging from roots, stems, leaves, until all fruit is of great value and can be used as a medicine for the health as well as from different tribe who were in Indonesia. Since old time sub etnic Kutai using different types of plants as a medicine because the lack of medical personnel and health care center in curing diseases. This study aims to find out the types of medicinal herbs used by tribes. The results there were 39 Medicinal plants used by tribes that is Serai, Sirih, Tumbuh daging, Kepius, Patah tulang, Kunyit root, Senuru , Mali wood, Prepat wood, lupun root, Kecubung, Terung pipit, Gelinggang, Beribit grass, Syurga leaf, Tapis bongol, Nyiur ongo, Singgah bini wood, Penggel habeng, Serkemudi grass, Tunjuk langit root, Kemet hitam, Pacar beleng, penggel putih, Ketotol grass, Kemantrah, Sahung wood, Tajerebo, Cula adem, Risip leaf, Lalang, Sampai root, Cancut haji jewa, Mersesat leaf, Lekop leaf, Kuku tupai, Kempis root, Kemet putih and Kedeme Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/54 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 107-110 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 1 (2016): Jurnal Ilmiah Manuntung; 107-110 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/54/52 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/55 2021-01-31T08:10:00Z jim:ART

PENETAPAN KADAR PROTEIN TEMPE JAGUNG (Zea mays L.) DENGAN KOMBINASI KEDELAI (Glycine max (L.) Merill) SECARA SPEKTROFOTOMETRI SINAR TAMPAK Jubaidah, Siti Nurhasnawati, Henny Wijaya, Heri Zea mays (Glycine max (L.) soybean protein Farmakognosi Indonesian is still very dependent of soybean imports, so as to reduce the use of soybean need to find substitute materials in the manufacture of soybean. Corn can be an option because apart from being a source of carbohydrates, corn is also an important source of protein in the menu society in Indonesia. The purpose of this study to determine the levels of soybean protein maize (Zea mays) with a combination of soybean (Glycine max (L.) Merrill) with visible of spectrophotometry. The research design uses a comparison of corn: soybean as follows: P1 = 80: 20; P2 = 70: 30; P3 = 50: 50; P4 = 30: 70 and P5 = 20: 80. The results of this study indicate that P1 has a protein content of 6.7%, P2 = 8.06% = 10.76% P3, P4 and P5 = 13.46% = 14.8%. The greater the concentration ratio of soy protein obtained even greater. In organoleptic quality in soybean corn combination has the texture a little hard to hard, has no smell until the typical aroma smelled soybean, flat white to brown of white Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/55 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung; 111-119 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 1 (2016): Jurnal Ilmiah Manuntung; 111-119 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/55/53 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/56 2021-01-31T07:59:09Z jim:ART

PERSEPSI MASYARAKAT TERHADAP DAMPAK KESEHATAN DARI AKTIVITAS PENAMBANGAN BATUBARA DI KAMPUNG TASUK KABUPATEN BERAU Mursyidin, Musyidin Warnida, Husnul coal mining health impact kampung Tasuk Berau public perception costumer satisfaction index Kesehatan Masyarakat Mining is an ancient occupation, long recognized as being arduous and liable to injury and disease. Coal mining carried dangers from exposure to noise, heat, and airborne dusts, causing many associated diseases. Respiratory diseases caused by coal mine dust are pneumoconiosis, chronic bronchitis, and emphysema. The process of coal mining involves the discharge of huge amount of effluent into the surface water. Effluent from coal mine contains high load of TSS, TDS, calcium carbonate and heavy metals accumulates in water, soil, sediment and living organism. Coal mining has long been established in East Kalimantan. This paper explores the public perceptions of the health and environmental impact of opencast coal mining in Kampung Tasuk, Gunung Tabur, Regency of Berau, East Kalimantan. The obtained result may be used as an input to formulate and redesign the community development program of coal mining company in Berau. The public perception of coal mining activity in kampung Tasuk was dissastified with costumer satisfaction index 58.1 Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/56 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung; 120-130 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 2 (2016): Jurnal Ilmiah Manuntung; 120-130 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/56/54 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/57 2021-01-31T07:59:24Z jim:ART

UJI AKTIVITAS ANTIDIARE EKSTRAK ETANOL 70% KULIT BUAH JENGKOL (Archidendron pauciflorum (Benth.) I.C.Nielsen) TERHADAP MENCIT JANTAN YANG DIINDUKSI OLEUM RICINI Rizal, Mohammad Yusransyah, Yusransyah Stiani, Sofi Nurmay Pithecellobium lobatum Benth antidiarrheal Oleum ricini Farmakognosi Plants that can be used as a medicinal plant one of which is Jengkol (Archidendron pauciflorum (Benth.) IC.Nielsen.). Seeds, bark and leaves jengkol contains saponins, flavonoids and tannins. The purpose of this study was to test the antidiarrheal activity of 70% ethanol extract of the fruit peel jengkol (Archidendron pauciflorum (Benth.) ICNielsen) to male mice that includes a solution of distilled water as a control, loperamide as a comparison, the ethanol extract of the fruit peel jengkol as test material, and oleum ricini as inductors. Research method used laboratory experiments. Data were analyzed by ANOVA (Analysis of Variance) and continued with different test average – average Duncan using SPSS (Statistical Product and Service Solutions). The results of that study 70% ethanol extract of the fruit peel jengkol (Archidendron pauciflorum (Benth.) IC Nielsen) provide nonspecific antidiarrheal activity. The content of the metabolites were present in 70% ethanol extract of the fruit peel jengkol (Archidendron pauciflorum (Benth.) IC Nielsen) which provides non-specific activity as antidiarrheal are tannins, flavonoids and steroids. Ethanol Extract Fruit Leather Jengkol 1.2 mg / g has a stronger effect in reducing diarrhea and provide optimum activity as nonspecific antidiarrheal. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/57 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung; 131-136 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 2 (2016): Jurnal Ilmiah Manuntung; 131-136 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/57/55 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/58 2021-01-31T07:59:46Z jim:ART

STUDI KELENGKAPAN PENJELASAN CARA PENGGUNAAN SEDIAAN CONTROLLER INHALER (KOMBINASI KORTIKOSTEROID DENGAN BETA-2 AGONIS) JENIS DISKUS® DAN TURBUHALER® OLEH APOTEKER DI APOTEK Lorensia, Amelia Queljoe, Doddy De Karina, Bella Lony Heru, Astri completeness how to use inhalers Diskus® Turbuhaler® pharmacist Farmasetika Asthma is a chronic disease that can be controlled by treatment with a controller containing a corticosteroid combination with beta-2 agonists, which are available in the form Diskus® and Turbuhaler® which is DPI (dry powder inhaler) in Indonesia. Techniques improper use can give less than optimal results, therefore, the role of pharmacists to provide education in the form of how to explain the inhaler. This study aims to find out information on how to use Diskus® and Turbuhaler® by pharmacists to patients with asthma in the pharmacy area of the city of Surabaya. This research is non-experimental research with cross sectional method, and using observation techniques in the form of a checklist. Sampling by non-random sampling method by using purposive. The data will be processed with descriptive statistical analysis. Based on the results of research on the use of information studies preparation Diskus® explanation is given, it can be concluded there is no pharmacist in the category optimal technique that is able to mention all the steps properly. Most pharmacists categorized adequate technique for the pharmacist is able to name all of the critical step. While on how to use Turbuhaler® information provided by pharmacists in explaining Turbuhaler to patients in pharmacies is still lacking for by an explanation of each step are not all pharmacists can explain all the steps correctly and based on the critical step yet pharmacists who achieve adequate and optimal techniques. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/58 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung; 137-146 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 2 (2016): Jurnal Ilmiah Manuntung; 137-146 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/58/56 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/59 2021-01-31T08:00:04Z jim:ART

UJI EFEK ANALGESIK EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura L.) PADA MENCIT PUTIH JANTAN (Mus musculus) DENGAN INDUKSI NYERI ASAM ASETAT Sentat, Triswanto Pangestu, Susiyanto Muntingia calabura L. Analgesic Mus musculus Acetic Acid Induced number of Writhing Farmakognosi Kersen leaf (Muntingia calabura L.) contains tannins, flavonoids and polyphenol compounds allegedly have analgesic effect. The objective was to determine the analgesic effect of ethanol extract of kersen leaves and to determine the most effective analgesic dose. This study was an experimental research. Leaves were extracted with ethanol 70% and the analgesic effect test was divided into 5 groups: negative control treatment (distilled water), positive control (mefenamic acid 2.6mg/kg), kersen leaf ethanol extract first dose (100mg/kg), second dose (200mg/kg) and tthird dose (400mg/kg). Giving treatments by oral, after 30 minutes, the mices were given a pain inductor with 0.5% acetic acid by intra peritonial administration. Analgesic power was calculated by counting the number of writhing in mice for 1 hour. The results showed that the ethanol extract of cherry leaf has analgesic effect. From the calculation of the first dose analgesic power (42.9%), second dose (59.4%) and the third dose 69.9%. Statistical test results kruskal wallis value of p=0.011 (p<0.05) showed a significant difference between all analgesic treatment groups. The conclusion of this study is all of the ethanol extract had analgesic effects on male white mice, whereas a dose of 400mg/kg is the most effective analgesic dose. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/59 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung; 147-153 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 2 (2016): Jurnal Ilmiah Manuntung; 147-153 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/59/57 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/60 2021-01-31T08:00:19Z jim:ART

UJI AKTIVITAS EKSTRAK ETANOL BIJI PINANG (Areca catechu L.) TERHADAP PENYEMBUHAN LUKA BAKAR PADA KULIT PUNGGUNG MENCIT PUTIH JANTAN (Mus musculus) Handayani, Fitri Sundu, Reksi Karapa, Henriko Nober Areca catechu burn wound wound surface area Farmakognosi Areca seeds contain flavonoid, tannin, and alkaloid which can help the healing process of burn wounds on the back skin of mice. Areca seeds are used for treatment because it has  antimicrobial activity. Areca Seeds are one of Indonesian plants which the fruit in tranditional way is used as burn medicine. The objective of this study was to know theeffect of ethanol extract of areca seeds against burn wound healing on the back skin of mice. Fifteen mices were used in this experiment and were divided into 5 groups : vaseline flavum as a control negative, branded ointment as a control positive , ethanol extract of areca seeds in vaseline flavum with consentration 20%, 40 % and 60 %. Each group consisted of 3 mices. The back skin of mice was induced using hot iron size 1×1 cm for 2 seconds then given a treatment for 14 days. The percentage of healing of burns  by calculating the surface area of wound. The results of its preliminary phytochemical analysis showed the presence of alkaloids, flavonoids, tannins and saponins. The percentage of burn wound healing of ethanol extract in concentration 20 % was 84,33 %, 40 % was 87,67%; and 60% was 89,67%. Data was analyzed using one-way Analysis of Variance (ANOVA) which showed that data has significant differences (P < 0,05) was 0,000. LSD test showed that each treatment group had siginicant differences with significant value < 0,05.   Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/60 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung; 154-160 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 2 (2016): Jurnal Ilmiah Manuntung; 154-160 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/60/58 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/61 2021-01-31T08:00:32Z jim:ART

UJI TOKSISITAS AKUT EKSTRAK ETANOL AKAR KB (Coptosapelta tomentosa Valeton ex K.Heyne) DENGAN METODE Brine Shrimp Lethality Test (BSLT) Supriningrum, Risa Sapri, Sapri Pranamala, Vici Ali KB root Toxicity Brine Shrimp Lethality Test LC50 Probit Analysis Farmakognosi The roots of KB plants (Captosapelta tomentisa) is used empiricallyby  Dayak Kenyah community as a drug leukorrhea. Leukorrhea is one of the early symptoms of cervical cancer. Early methods to determine the LC50 value or toxicity of anticancer KB roots have not been reported. The aim of research is to determine the value of the toxicity of KB root. Research was conducted by an experimental study. Research stages include sample processing, extraction and acute toxicity test by Brine Shrimp Lethality Test (BSLT). BSLT testing to determine LC50 values with a concentration of 250 ppm, 300 ppm, 400 ppm, 450 ppm and a negative control. Analysis of the data used are probit analysis method. The results showed  the presence of flavonoids, alkaloids and saponins in of the ethanol extract of KB root . The test results obtained acute toxicity LC50 value is 299.226 mg / ml, so that the ethanol extract of roots KB potentially toxic to the larvae of Artemia salina Leach. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/61 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung; 161-165 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 2 (2016): Jurnal Ilmiah Manuntung; 161-165 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/61/59 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/63 2021-01-31T08:00:51Z jim:ART

UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN KEREHAU (Callicarpa longifolia Lam) TERHADAP Escherichia coli dan Staphylococcus aureus Kusumawati, Eko Apriliana, Anita Khatimah, Khusnul Callicarpa longifolia Lam antibacterial disc diffusion Escherichia coli Staphylococcus aureus Farmakognosi Kerehau (Callicarpa longifolia Lam) is a plant that has traditionally efficacious as a cure colds and diarrhea. Part used as medicine are the leaves. This study aims to determine the antibacterial activity of ethanol extract of leaves kerehau on Escherichia coli and Staphylococcus aureus. Kerehau leaf extract prepared by maceration method using ethanol 70%, with a test concentration of 10%, 25%, 50%, and 100% and chloramphenicol 0.1% (w / v) as a positive control and dimethyl sulfoxide 1% (v / v) as a negative control. The results of antibacterial activity test with extract concentrations of 25%, 50% and 100% in Escherichia coli is 9.45 mm, 12.21 mm and 17.38 mm, for the positive control is 21.85 mm. The results of antibacterial activity test with extract concentrations of 10%, 25%, 50% and 100% in Staphylococcus aureus was 7.3 mm, 9.85 mm, 13.65 mm and 20.58 mm, for the positive control was 24.05 mm. The antibacterial activity was analyzed by One Way ANOVA showed significant differences between treatments Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/63 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung; 166-172 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 2 (2016): Jurnal Ilmiah Manuntung; 166-172 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/63/60 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/64 2021-01-31T08:01:06Z jim:ART

PENENTUAN KADAR RESIDU TETRASIKLIN HCl PADA IKAN AIR TAWAR YANG BEREDAR DI PASAR SEGIRI MENGGUNAKAN METODE SPEKTROFOTOMETRI ULTRA VIOLET Nurhasnawati, Henny Jubaidah, Siti Elfia, Novita Fish Tetracycline HCl residue Standard addition UV spectrophotometry Kimia Tetracycline HCl is one of the most commonly used antibiotics in fish farming that aims to control diseases caused by bacteria. The purpose of this study was to determine the presence and the level of tetracycline HCl antibiotic residue in freshwater fishes sold at the Segiri traditional market. The method used in this research was a standard addition ultraviolet spectrophotometry. The results showed that residue level of tetracycline HCl in freshwater fish is 192,067 μg/g – 257,409 μg/g. These result was far exceeded the maximum residue level of tetracycline class antibiotics in meat and dairy based on SNI 01-6366-2000 that limit the residue not higher than 0.1 μg/g Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/64 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung; 173-178 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 2 (2016): Jurnal Ilmiah Manuntung; 173-178 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/64/61 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/65 2021-01-31T08:01:24Z jim:ART

UJI TOKSISITAS AKUT KAPSUL BAWANG PUTIH LANANG (Allium sativum Linn) Murtisiwi, Lusia Lindawati, Novena Yety Allium sativum Linn dried extract garlic toxicity test phytopharmaca Farmakognosi Garlic (Allium sativum Linn) is evidently active against Mycobacterium tuberculosis. Garlic contains allicin that is able to inhibit the bacteria causing tuberculosis. This dried extract garlic is also qualified as content of capsules of traditional medicine, score of Total Plate Count is1.5 (required not over 10); figures of mold and yeast extract of garlic is 4.102 (required not over 104); does not contain microbial pathogens (uncontaminated with coliform bacteria, Escherichia coli, Salmonella sp, and Staphylococcus aureus); and aflatoxin is not detected (required not more than 30 CPM); the average of moisture content is 2% (required notmore than 10%). Capsule of dried extract garlic (Allium sativum Linn) meets pharmaceutical requirements for traditional medicine capsule dosage form, with9 minutes as disintegrating time (required not more than 15 minutes) and meets the uniformity of weight as required for capsule. Results of the research indicates that dried extract of garlic indose above 48.750 mg/ kg body weightto get LD50in garlic, belongs to ‘relatively harmless’. Dried extract garlic in 4 doses variations do not affect the liver functions of mice, so significant clinical toxicity symptoms that happen on entire animals test have not gained yet Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/65 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung; 179-188 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 2 (2016): Jurnal Ilmiah Manuntung; 179-188 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/65/62 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/66 2021-01-31T08:01:40Z jim:ART

UJI EFEKTIFITAS FORMULA SPRAY DARI MINYAK ATSIRI HERBA KEMANGI (Ocimum Sanctum L ) SEBAGAI REPELLENT NYAMUK Aedes aegypti Aini, Resmi Widiastuti, Rina Nadhifa, Nuha Afra herb basil spray repellent Farmakognosi Dengue fever is transmitted by the bite of Aedes aegypti mosquitoes infected with denguevirus. Preparations antinyamuk much use of harmful chemicals such as DEET (diethylmetatoluamide) and permethrin that can lead to pollution of the environment, leavingno residue and cause resistance to the drug. To determine the activity of essential oils from herbs basil (Ocimum Sanctum L) in the preparation of spray as a mosquito repellent and determine the effective concentrationof the spray.This type of research is True experiment with design Post Test Only Control Group Design. Repellent activity was observed by means of spray is sprayed on the back of the hand probandus, then tested on female mosquitoes with the introduction into the cage containing20 mosquitoes each treatment. Spray essential oils showed repellent activity of Aedes aegypti with a value of correlation r = 0.964 higher concentration of essential oils the fewer mosquitoes that land. Spray herbal essential oil of basil (Ocimum basilicum L) has a repellent activitycompared to the negative control. The effectiveness of the herb basil essential oil sprayobtainedat 74.131 ppm lC50 and lC90 of  775.711 ppm Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/66 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung; 189-197 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 2 (2016): Jurnal Ilmiah Manuntung; 189-197 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/66/63 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/67 2021-01-31T08:01:53Z jim:ART

POTENSI TONGKOL JAGUNG (Zea Mays L.) SEBAGAI SUNSCREEN DALAM SEDIAAN HAND BODY LOTION Ekowati, Dewi Hanifah, Inaratul Rhizky corn cob lotion stability of cream Sunscreen Farmakognosi The over exposure sunlightis on the skin provides of damage. Skin damage caused the over exposure sunlightis can occur in the short term such as erythema or long term such as premature skin aging and even skin cancer. One way that can be done to minimize the amount of UV that penetrated into the skin is to use sunscreen. Corn cob contain the chemical compounds of phenolic, which suspected to have the protection activity toward the UV B rays. The study aims to make preparations hand body lotion that meet good physical quality of the corn cob extract  as a sunscreen. Hand made three body lotion formula with extract concentrations of corn cob 10% FI, FII FIII 15% and 20%. Testing the physical properties of the test hand body lotion include viscosity, dispersive power and pH. The effectiveness of a sunscreen is based on a determination of the value of the Sun Protection Factor (SPF) in vitro. The third formula has a good physical quality lotion that viscosity 50-1000 dPas, the scatter 5-7 cm, pH 4.5 -7. The effectiveness of sunscreen based on the value of the Sun Protection Factor (SPF), the effectiveness FIII in the category of extra protection is 7.23. SPF value FI  FII 5.13 and 5.67 so that FI and FII into the category of moderate protection Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/67 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung; 198-207 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 2 (2016): Jurnal Ilmiah Manuntung; 198-207 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/67/65 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/68 2021-01-31T08:02:12Z jim:ART

PENGARUH PERBEDAAN CHEMICAL PENETRATION ENHANCER PADA PENETRASI TRANSDERMAL PATCH PROMETAZIN HCL Nurahmanto, Dwi patch prometazin HCl penetration enhancer transdermal Kimia This research aims is to create a promethazine HCl patch transdermal drug delivery systems with the most excellent penetration. Transdermal drug delivery can be efficiently used for the active agents which undergo rapid first pass metabolism and oral absorption is often disrupted by nausea and vomiting, hence the transdermal patches of promethazine HCl were prepared by using different penetration enhancers,  propylene glycol, oleic acid and isopropyl alcohol. The prepared formulations were evaluated for thickness, weight variation, moisture content, drug content, morphology, and in vitro permeation studies. The patch morphology studies were performed by Scanning Electron Microscopy (SEM). The amount of promethazine HCl transfered by propylene glycol  25.77 ± 3.0396 ug, isopropil alcohol 25.758 ± 2.9022 ug and oleic acid 25.017 ± 8.1300 ug. The penetration of promethazine HCl patch with oleic acid enhancer, produce the highest penetration than isopropil alcohol and propylene glycol. there was no difference in penetration using propylene glycol and isopropyl alcohol. Oleic acid is the best enhancer for preparations patch containing promethazine HCl although the amount of promethazine HCl contained is the least. The whole formulations comply with the  patch dosage requirements Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/68 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung; 208-217 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 2 (2016): Jurnal Ilmiah Manuntung; 208-217 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/68/66 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/69 2021-01-31T08:02:27Z jim:ART

VALIDASI METODE ANALISIS DAN PENURUNAN KADAR INFUS CIPROFLOKSASIN YANG DIPENGARUHI REAKSI OKSIDASI MENGGUNAKAN HPLC Nugraheni, Bekti Nafi'ah, Nafi'ah Anggoro, B Validation ciprofloxacin infusion HPLC oxidation reaction Kimia Validation of analysis methods is conducted on the assay of the antibiotic ciprofloxacin because it is often used in the treatment of urinary tract infections, respiratory tract infections and gastrointestinal infections. This study aimed to determine the validity of an analytical method. Development of methods used in this study were the mobile phase of methanol: aquabidest : 0.1 M phosphate buffer: acetonitrile (80: 10: 5: 5). Then the ciprofloxacin validation was performed. After the methods validation were valid, the assay of ciprofloxacin in infusion was performed to determine the decreased levels which affected by the oxidation reaction of 0, 60, 90, 150 and 180 minutes. The validation parameters in the research were selectivity, accuracy, precision, linearity, LOD and LOQ. Samples were standart ciprofloxacin used for the validation and infusion of ciprofloxacin for the assay on the sample application that was affected by the oxidation reaction. The used of HPLC met the requirements such as HPLC devices Waters e2695 Separations, SunFireTM column C18, and PDA detector and a flow rate of 1.0 mL / min. This study showed that the result was selective, stated with no emergence of peaks in the matrix. HPLC analysis methods on ciprofloxacin meet the acceptance criteria of accuracy % recovery value solution concentration of ≥10 mg / mL are 90-107%. Precision test qualifies % RSD for solution concentrations ≥10 mg / mL is <7.3%. Linearity r ≥0,997 then it can be concluded that the result was qualified. LOD value is 0.2707 µg / mL and the LOQ value is 0.9026 µg / mL. The results of the assay infusion of ciprofloxacin were found that there was a significant decrease in the levels of ciprofloxacin due to the influence of the oxidation reaction Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/69 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung; 218-223 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 2 (2016): Jurnal Ilmiah Manuntung; 218-223 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/69/67 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/70 2021-01-31T08:02:47Z jim:ART

FORMULASI SEDIAAN SALEP EKSTRAK ETANOL DAUN ALPUKAT (Persea americana Mill.) SEBAGAI ANTIACNE Soemarie, Yulistia Budianti Astuti, Tri Rochmah, Nur Persea Americana. Mill. Anti-Acne Physical Stability Ointment Farmakognosi Currently, the development of acne drugs (antiacne) use  many natural materials because the natural materials can minimize the side effect if compared with synthetic chemicals drugs. Acne can caused by propionibacterium acnes, staphylococcus epidermis and staphylococcus aureu. One of plants that can be used for acne treatment is leaves of Avocado (Persea americana Mill). The aim of this study was to know whether the ethanol extract of leaves of avocado (Persea americana Mill.) can be made into an ointment preparations that fulfill the requirements. Sample in this research was extract of avocado leaves which used maceration method. The ointment formulations were made into some variation concentrations of PEG 400 and PEG 4000: Formula I (30%:70%); Formula II (50%:50%) and Formula III (70%:30%). The results show that the ointment of avocado leaves which fulfilled the requirements of physical properties is formula III with concentration of PEG 400 70 % and PEG 4000 30 % Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/70 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung; 224-232 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 2 (2016): Jurnal Ilmiah Manuntung; 224-232 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/70/68 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/71 2021-01-31T08:03:05Z jim:ART

FORMULASI PATCH KOSMETIK LENDIR BEKICOT (Achatina fulica) DENGAN POLIMER KITOSAN DAN BERBAGAI VARIASI AMILUM Nisa, Michrun Nuraisyah, Andi Yusuf, Nurul Arfiyanti K, Nurul Alifah snail slime starch cosmetic patches Farmakognosi The research on cosmetic patch formulation containing snail slime with a variety starch was aimed to determine the type of starch that could produce a patch preparation with a good physical characteristic had been conducted. Cosmetic patch formulation of snail slime was using combination of chitosan and starch polymers such as corn, potato and tapioca starch. The method was used the solvent evaporation technique. The evaluation of patches include weight uniformity, folding endurance, thickness, moisture content, moisture uptake and stability of the patch. The combination of chitosan and starch polymers produced patches that had pH 5 with color uniformity, smoothness of surface and easily removed from the mold. The results showed that patches containing tapioca starch gave weight uniformity that did not much different on each replication that was 0,568 ± 0,03. Patches containing corn starch provided thickness values on each replication did not much different from 0,16± 0,01. Patches containing potato and tapioca starch produced patches that was accordance with the standard parameter of folding endurance was more than 200 times. Patches containing corn and tapioca starch producing patches accordance with the standard parameter of moisture content were less than 10 %. Patches containing potato starch gave patch a high moisture uptake that was 8,2%. The combination of chitosan and tapioca strach as polymers produced patch preparation with a good characteristic on the formulation of snail slime cosmetic patch. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/71 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung; 233-238 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 2 (2016): Jurnal Ilmiah Manuntung; 233-238 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/71/69 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/72 2021-01-31T08:03:21Z jim:ART

UJI AKTIVITAS ANTIBAKTERI FORMULASI GEL UNTUK SARIAWAN DARI EKSTRAK DAUN SAGA ( Abrus precatorius Linn. ) TERHADAP BAKTERI Staphylococcus aureus Pertiwi, Ratih Dyah Kristanto, Joni Praptiwi, Graha Ayu saga leaves gel antibacterial activity Farmakognosi One of plants used by Indonesian people as a traditional medicine is saga plant (Abrus precatorius L.). This plant has medicinal properties as medication for thrush, cough and laryngitis. Chemical constituents contained in sage leaves which work as antibacterial are flavonoid and saponin. This study aims to determine the optimal concentration of saga leaves extract which can be formulated in a gel dosage form with qualified physical evaluation and has antibacterial activity against Staphylococcus aureus. Saga leaves extract is prepared by maceration method using ethanol 70% as solvent, and then the extract obtained is preliminarily tested to see its antibacterial activity against Staphylococcus aureus with agar diffusion method. Gel formulation for thrush is made with dispersion method in three formulas with variants of active substance concentration that is FI (1%), FII (3%) and FIII (5%). Gel preparation antibacterial activity test is conducted with agar diffusion method as a plate cylinder. Based on this research, it was found that the extract of saga leaves which is positively made is efficacious as antibacterial and can be formulated into a gel preparation for thrush with optimal concentration in F III (5%), this is indicated by widest diameter of the inhibition area against Staphylococus aureus bacteria Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/72 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung; 239-247 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 2 (2016): Jurnal Ilmiah Manuntung; 239-247 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/72/70 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/73 2021-01-31T08:03:44Z jim:ART

UJI CEMARAN BAKTERI COLIFORM PADA MINUMAN AIR TEBU Sukawaty, Yullia Kamil, Muhammad Kusumawati, Eko sugarcane juice coliform Most Probable Number (MPN) Kimia Sugarcane juice beverage is a beverage that is found along the village Sempaja and Pelita roads. Contamination in processed beverages derived from sugarcane juice and equipment used allow for contamination by coliform bacteria. The purpose of this study to investigate the contamination of coliform bacteria in water beverage sugar circulating in the village Sempaja and Pelita. Tests using the Most Probable Number (MPN) includes test estimators using lactose broth as the presumptive medium and Brillian Green Lactose Bile Broth as the confirmad medium. The results showed that eight samples tested positive for coliform contaminated with a high of 2800×101 MPN / mL (sample H) and the lowest value 170×101 MPN/mL (sample D). The results obtained show that the sugarcane juice drinks that supply does not meet the standards of Rule Head POM HK.00.06.1.52.4011 No. 2009 with standard quality requirements of 2×101colonies/mL. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/73 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 2 No 2 (2016): Jurnal Ilmiah Manuntung; 248-253 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 2 No. 2 (2016): Jurnal Ilmiah Manuntung; 248-253 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/73/71 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/84 2021-01-31T07:53:22Z jim:ART

IDENTIFIKASI SENYAWA METABOLIT SEKUNDER DAN UJI AKTIVITAS EKSTRAK ETANOL HERBA MENIRAN (Phyllanthus niruri L.) TERHADAP CANDIDA ALBICANS MENGGUNAKAN METODE DIFUSI CAKRAM Apriliana, Anita Kusumawati, Eko Selvitawati, Selvitawati The aim of this research is to know the ability of meniran ethanol extract (Phyllanthus niruri L.) in inhibiting the growth of Candida albicans. The research design is an experimental study. The extract used was herbal meniran extract made by maceration using 70% ethanol solvent, the content of ethanol extract of meniran tested against Candida albicans using disc diffusion method were 5%, 10%, 20%, 30% and 40%. Activity test conducted on Sabaraound Dextrose agar media that has been smeared with Candida albicans culture which has been standardized with Mc Farland standard. The pre-tested disc paper is first dipped into the extract with various concentrations. Incubated at 30 ° C for 24 hours and the inhibit zone formed was measured. The result showed that herbal ethanol extract of meniran resulted in drag zone diameter at Candida albicans ie 8,5 mm; 10.3 mm; 12.6 mm; 14.1 mm and 14.3 mm, for negative control 0 mm and positive control 20.1 mm. Data obtained from the results of the study were analyzed using one way anova method showed p - value <0,05, it was concluded that there was significant difference between negative control, 5%, 10%, 20%, 30%, 40% and positive control. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-06-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/84 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung; 1-6 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 1 (2017): Jurnal Ilmiah Manuntung; 1-6 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/84/73 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/85 2021-01-31T07:53:35Z jim:ART

HUBUNGAN PELAYANAN INFORMASI OBAT TERHADAP KEPATUHAN MINUM OBAT PASIEN HIPERTENSI DI RSUD PENAJAM PASER UTARA Sentat, Triswanto The Drug Information Service or Pelayanan Informasi Obat (PIO) is indispensable for improving patient compliance with their treatment. With the PIO can change the knowledge and compliance of patients, especially hypertensive patients. This study was conducted to determine whether PIO can influence adherence to medication hypertension patients in RSUD Penajam Paser Utara. Sampling was done by purposive sampling and analyzed using Spearman Rank Correlation Test where the compliance aspect was assessed using validity and reliability tested questionnaire method, given before PIO and after PIO, and Pill Count method (calculating the remaining pills for 4 weeks) . Samples were obtained by 50 people, the results showed no improvement in adherence before and after PIO administration, and there was a relationship of compliance measurement results with questionnaire method after counseling and Pill Count method. The percentage of patient adherence after PIO administration was based on a high-compliance 70% (35 person) questionnaire method and based on the Pill Count method with a high adherence rate of 60% (30 persons), the compliance data obtained from both methods indicated that the provision of PIO can not improve compliance to take medication of hypertension patient of RSUD Penajam Paser Utara Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-06-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/85 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung; 7-13 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 1 (2017): Jurnal Ilmiah Manuntung; 7-13 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/85/74 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/86 2021-01-31T07:53:51Z jim:ART

STUDI KELENGKAPAN PENJELASAN INFORMASI CARA PENGGUNAAN CONTROLLERMETERED-DOSE INHALER (MDI) YANG MENGANDUNG KORTIKOSTEROID SEBAGAI TERAPI ASMA DI APOTEK KABUPATEN TUBAN Lorensia, Amelia Nathania, Jessica This experiment centred in metered dose inhaler (MDI) device which used routinely by asthma patient as controller therapy. MDI used ask patient’s skill more when using their medication. MDI technique informnation provided by pharmachist are important to achive optimal medication in asthma therapy. By a non experimental study, mysterious patient collect MDI technique gived by pharmacist in Tuban pharmacy using observacional and cross sectional method. Information about MDI technique comprehensive collected by two ratter as mysterious patient which assessed with checklist that got measseured by kappa to know ratter aggrement percentage. The result showed from a total sampling under 41 pharmachist which represent each 41 pharmacy in Tuban, by purposive sampling Pharmacists as pharmaceutical personnel responsible for information services at pharmacies, including information on how to use MDI. Most of the apothecary's ability level in providing information is still lacking, then continued with adequate technique, and optimal technique in providing complete information of MDI use for asthma patient. Pharmacists know how to use MDI and no pharmacist is unexpected or not familiar with MDI as an asthma therapy. Pharmacists in Tuban district have a tendency to inform only four stages of the nine stages of MDI use from Osman et al (2012), ie at the 1st, 3rd, 5th, and 6th stages of MDI use Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-06-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/86 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung; 14-25 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 1 (2017): Jurnal Ilmiah Manuntung; 14-25 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/86/89 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/87 2021-01-31T07:54:08Z jim:ART

DETEKSI Staphylococcus aureus dan Salmonella PADA JAJANAN SIRUP Puspadewi, Ririn Adirestuti, Putranti Abdulbasith, Afif Microbial on food are caused by various factors such as nutrients, water, and temperature. If total amount of microbes increase it would damage food and if it ingested could affect grastrointestinal track. Snack, especially unregistered snack such as syrup in school is one of important problem to concerned. The purpose of this study is to detect the present of Staphylococcus aureus and Salmonella in syrup in four elementary schools in Cimahi. Detection of Staphylococcus aureus is done using BPA medium, while detection of Salmonella is using Indol test, methyl red test, Voges Proskauer test, Citrate test and Gram staining. The result shows that the syrup from the elementary school contains Staphylococcus aureus but not all of samples of syrup give positive result of Salmonella. Based on the requirements which in set in SNI that microbes in syrup should not be contain to Staphylococcus aureus is negative/ml and Salmonella is negative/25 ml, then syrup that sold in all four elementary schooldi not qualified. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-06-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/87 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung; 26-33 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 1 (2017): Jurnal Ilmiah Manuntung; 26-33 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/87/76 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/88 2021-01-31T07:54:27Z jim:ART

PENGARUH LAYANAN PESAN SINGKAT PENGINGAT TERHADAP KEPATUHAN KONSUMSI OBAT PASIEN DM TIPE 2 DI PUSKESMAS MELATI KABUPATEN KAPUAS Susanto, Yugo Alfian, Riza Riana, Rinidha Rusmana, Ibna Diabetes mellitus is a chronic disease characterized by hyperglycemia and glucose intolerance. Patients with DM in Indonesia ranks 4th largest with a prevalence of 8.6 % of the total population. Patient compliance in the treatment greatly affect the success of the therapy. The purpose of this study was to determine the level of adherence before and after administration of short message reminders, as well as knowing the adherence changes that occur in patients with type 2 diabetes at the Puskesmas Melati Kabupaten Kapuas. This esearch was conducted by quasi experimental design, with prospective data collection during the period from May to June 2016. The intervention was giving short message service reminder. Subjects who met the inclusion criteria as many as 15 patients. The primary data collection is done by filling the questionnaire adherence MMAS and secondary data obtained from medical observation sheet.            The results showed that in the pre intervention average value (mean) adherence by 5.8 or are in the low adherence rate, in post intervention average value of 7.4 or adherence are moderate adherence rates, with the rate of change (Δ) adherence towards better at 1.6. It can be concluded that the adherence were lower before than after giving short message service reminder. There was improvement in the adherence to taking medicine after giving short message service reminder. The giving short message service reminder increased the adherence to take medicine effectively Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-06-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/88 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung; 34-42 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 1 (2017): Jurnal Ilmiah Manuntung; 34-42 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/88/77 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/89 2021-01-31T07:54:39Z jim:ART

PENGARUH ISOPROPIL MYRISTAT SEBAGAI BAHAN PENINGKAT PENETRASI TERHADAP LAJU DIFUSI KRIM PEMUTIH EKSTRAK ETANOL DAUN MURBEI (Morus alba L) Yusuf, Nurul Arfiyanti Fatmawaty, Aisyah The research has conducted research on the effectiveness of isopropyl myristat as a penetration enhancer on the diffusion rate of whitening cream mulberry leaf extract (Morus alba L) in vitro. This study aims to determine the effect of the use of isopropyl myristat. Mulberry leaf extract cream made with varying concentrations respectively 3%, 4%, 5% Isopropyl myristat as penetration enhancers made into 3 formulas (F1-F4) with the F1 without penetration enhancers. Evaluation of stability before and after accelerated storage includes observation of the organoleptic, emulsion type determination, measurement of pH, and viscosity. The evaluation results indicate four physically stable formula. In vitro diffusion studies conducted by Franz diffusion cells and footage is measured at a wavelength of 367.4 nm. The results of diffusion studies show that formula with the highest diffusion rate of 0.024 µg/minute on F4 (5% isopropyl myristat). Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-06-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/89 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung; 43-51 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 1 (2017): Jurnal Ilmiah Manuntung; 43-51 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/89/78 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/90 2021-01-31T07:54:57Z jim:ART

STATUS KELENGKAPAN IMUNISASI HEPATITIS B PADA USIA 0-6 BULAN DENGAN KEJADIAN HEPATITIS B Widia, Lidia Immunization is a process to make the body's immune defense system against invading microorganisms (bacteria and viruses) that can cause infections before these microorganisms have a chance to invade our bodies. Hepatitis B immunization is the immunization to prevent the body less susceptible to hepatitis B virus. The purpose of this study was to identify whether there is the Relationship Between Hepatitis B Immunization Status Completed At Age 0-6 Month With Events Hepatitis B in the Work Area Puskesmas Perawatan Simpang Empat Kecamatan Simpang Empat Kabupaten Tanah Bumbu.This research method is analytical survey and cross sectional approach for studying the dynamics of the correlation between risk factors and the effects of the approach, observation or data collection at once at a time (point time approach), the sampling technique is taken with total sampling technique that met the inclusion criteria and exclusion of mothers with babies were recorded in the register Puskesmas Simpang Empat Kecamatan Simpang Empat Kabupaten Tanah Bumbu. The data obtained were analyzed using chi-square test with significance of 0.05. Chi-Square test results obtained there is a significant relationship between the completeness status of hepatitis B immunization (P = 0.005) with the occurrence of Hepatitis B, for the conclusion in this study found no relationship between the completeness status of hepatitis B immunization with Hepatitis B in Puskesmas Simpang Empat Kecamatan Simpang Empat Kabupaten Tanah Bumbu. It is hoped that no more infants are immunized against the completeness of incomplete hepatitis B immunization to reduce the incidence of hepatitis and reduce infant mortality Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-06-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/90 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung; 52-58 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 1 (2017): Jurnal Ilmiah Manuntung; 52-58 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/90/79 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/91 2021-01-31T07:55:09Z jim:ART

IDENTIFIKASI BAKTERI Escherichia coli PADA MINUMAN TEH KEMASAN INDUSTRI RUMAH TANGGA DI KELURAHAN SUNGAI DAMA DAN SELILI MENGGUNAKAN METODE MOST PROBABLE NUMBER (MPN) Handayani, Fitri Sundu, Reksi Dawia, Dawia Tea beverage packaging is a popular fast food beverage because it has a variety of flavors that are in great demand by the public. Presentation of packaged tea beverages is mostly found in roads that may be contaminated by Escherichia coli bacteria. This study aims to identify Escherichia coli bacteria in packaged tea drinks circulating in the rivers of Kelurahan Selili. This research is a descriptive research. The sample used is packaged tea drink taken in two subdistricts of Samarinda ilir namely Selili urban village and Sungai Dama by using Purposive Sampling method of 10 samples. Sample tests include presumtive test, confirmative test and completed test. The LB (Lactose Broth) assay test was used to detect early presence of Coliform bacteria, BGLBB (Brillian Green Lactose Bile Broth) as a detector of the specification of the presence of Coliform bacteria and completed test using EMBA (Eosin Methylene Blue Agar) as Escherichia coli. The results of this study were 7 samples of 10 samples tested containing Escherichia coli. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-06-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/91 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung; 59-63 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 1 (2017): Jurnal Ilmiah Manuntung; 59-63 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/91/80 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/92 2021-01-31T07:55:22Z jim:ART

UJI MUTU FISIK GRANUL EKSTRAK ETANOL DAUN KEMANGI (Ocimum americanum L.) DENGAN VARIASI KONSENTRASI EXPLOTAB® Soemarie, Yulistia Budianti Sa'adah, Hayatus Fatimah, Nurul Ningsih, Tri Marga Bad breath is usually caused by bacteria and food debris left in the mouth. Development of preparations using herbal ingredients, to overcome the problem of bad breath one of them is with utilization basil leaves (Ocimum americanum L.) which have anti bacterial activity. The method of wet granulation is a single method for use in granulation of large doses of active substances because if using direct induced method will require again the addition of a large number of fillers to make it easier forging, but cause the tablet to be not feasible as it will resulting in an increase in tablet size. The type of research conducted is an experimental study. Object the study was basil leaf extract formulated. This formulation was prepared by wet granulation method with variation Explotab® ss crusher ie 2%, 4%, 6% and 8%. Performed wet granulation on each formulation. Granul evaluated the flow time, mass density test, silent angle and fixed assay test. Based on research result the physical quality of ethanol extract granule of basil leaves (Ocimum americanum L.) with explotab® concentration variation it can be concluded that all the formula fulfill the good quality of granule characteristic, because it meets the requirements of parameters of time flow, rest angle, compressibility and density mass Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-06-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/92 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung; 64-71 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 1 (2017): Jurnal Ilmiah Manuntung; 64-71 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/92/81 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/93 2021-01-31T07:55:39Z jim:ART

FORMULASI DAN EVALUASI KRIM EKSTRAK BAWANG TIWAI (Eleutherine bulbosa) Warnida, Husnul Nurhasnawati, Henny Exposure of the skin to ultraviolet (UV) radiation from the sun has various adverse effects, photoaging and skin cancer are of great concern. The ability of botanical antioxidants for prevention of photocarcinogenesis and photoaging had been widely known. Bawang tiwai (Eleutherine bubosa) is traditionally used by the native people of Kalimantan for cancer treatment. The ethanolic extract of bawang tiwai originated from Banjarbaru district, South Kalimantan had strong antioxidant activity. The objective of the study was to formulate Eleutherine bulbosa extract into cream and evaluate its scavenging activity. Antioxidant activity of Eleutherine bulbosa cream was assessed by 2-diphenyl-1-picrylhydrazyl (DPPH) method. The Eleutherine bulbosa extract was incorporated into five cream formulas in varied concentration of emulsifying wax and cetyl alcohol. Evaluation of cream including physical appearance, pH, viscosity, stability, and microbial growth test. The result showed that Eleutherine bulbosa cream has antioxidant activity and good physicochemical quality Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-06-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/93 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung; 72-76 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 1 (2017): Jurnal Ilmiah Manuntung; 72-76 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/93/82 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/94 2021-01-31T07:55:51Z jim:ART

FORMULA DAN EVALUASI GEL PEMBERSIH TANGAN EKSTRAK BAWANG TIWAI (Eleutherine bulbosa (Mill.) Urb) Sukawaty, Yullia Apriliana, Anita Warnida, Husnul Bawang tiwai (Eleutherine bulbosa (Mill.) Urb.) acts as an antibacterial because it contains a class of alkaloids, flavonoids, saponins, tannins, glycosides, triterpinoida / steroid, anthraquinone glycosides.Bawang tiwai onions can be used as an antibacterial active ingredient formulated in a gel hand sanitizer. The purpose of this study to determine the effect of varying concentrations of alcohol on the physical properties of gel preparation and inhibition of E.coli bacteria which are formulated in the form of a gel hand sanitizer bawang tiwai extract. Research conducted on fomula gel hand sanitizer bawang tiwai extract with various concentrations of alcohol F1 0%, F2 10%, F3 20%, F4 60% include (organoleptic, homogeneity, pH, dispersive power, consistency and viscosity) and continued with test inhibition of E. coli using disc diffusion method (Kirby-Bauer) in F1 0%, 10% F2, F3 20%, K (-) 60% and K (+) Triclosan 0.1%. Data were analyzed with SPSS 16.0 using Kruskal Wallis test with a level of 95%, α = 0.05. Gel hand sanitizer contains bawang tiwai extract 20% meets the requirements of the physical stability and have antibacterial inhibition of E. Coli Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-06-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/94 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung; 77-82 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 1 (2017): Jurnal Ilmiah Manuntung; 77-82 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/94/88 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/95 2021-01-31T07:56:25Z jim:ART

FORMULASI TABLET EKSTRAK ANGKAK (RED YEAST RICE) DENGAN VARIASI CROSCARMELLOSE SODIUM SEBAGAI PENGHANCUR DAN LAKTOSA SEBAGAI PENGISI Resti, Adestria Kusuma, Aris Perdana Fudholi, Achmad Angkak or better known as Red yeast rice is fermentation rice using a mold Monascus purpureus. Some studies of red yeast rice can lower cholesterol levels in the body because it contains monoakolin K or similliar with lovastatin compound. Generally in community consumption of red yeast rice only with pour in the boilling water so it can causing inconvenience for its customers. This study aims to make a formulation tablet of red yeast rice extract which varied with the levels of croscarmellose sodium 5% -1% (32mg, 26mg, 19,5mg, 13mg, 6,5mg) and lactose (75,75mg, 82.25 mg, 88,75mg , 95,25mg, 101,75mg) in order to get a best physical properties of the tablet including friability and disintegration time. Angkak extract was made by remaseration method using ethanol 75% and the manufacture of tablets using wet granulation method. Stastical test tablet extract angkak using One Way ANOVA with 95% confidence level. Optimum formula obtained by using the Simplex Lattice Design (SLD) using Design Expert version 8.0.7.1 program and statistically tested using one-sample t-test. The results from test showed the proportion of croscarmellose sodium 6.5mg and 101.75mg lactose produces tablets with the best of physical properties of red yeast rice extract.The result is indicate that the combination of croscarmellose sodium and lactose may affect response the physical properties of red yeast rice extract tablets. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-06-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/95 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung; 83-90 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 1 (2017): Jurnal Ilmiah Manuntung; 83-90 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/95/84 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/96 2021-01-31T07:56:40Z jim:ART

PERBANDINGAN METODE EKSTRAKSI MASERASI DAN SOKLETASI TERHADAP AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN JAMBU BOL (Syzygium malaccense L.) Nurhasnawati, Henny Sukarmi, Sukarmi Handayani, Fitri Malay apple (Syzygium malaccense L.) is a plant that can be used for treatment. Antioxidants have the activity to reduce free radical compounds which is one of the causes of the emergence of various diseases in humans. The purpose of this study to determine the comparison of methods of maceration and socletation extraction of antioxidant activity of malay apple leaf. Research stages include sampling, plant determination, making of simplisia, maceration extraction and socletation with 70% ethanol solvent and determine the antioxidant activity by UV-Vis spectrophotometry with DPPH (1,1-diphenyl-2-picrylhydrazyl) as free radical. The parameter is IC50 value that is the concentration of antioxidant compound which can cause 50% loss of DPPH free radical activity. Although both methods show very strong antioxidant activity, it can be concluded that the difference in extraction methods has an effect on the antioxidant activity produced. The results of antioxidant activity test showed that socletation methods gave an average IC50 value of 37.67 ppm, this value is higher than maceration methods with an average IC50 value of 47.80 ppm. Malay apple leaf has the potential as a natural antioxidant, although it has a lower IC50 value than vitamin C which is 9.72 ppm. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-06-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/96 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung; 91-95 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 1 (2017): Jurnal Ilmiah Manuntung; 91-95 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/96/85 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/97 2021-01-31T07:56:53Z jim:ART

FORMULASI SEDIAAN GEL DISPERSI PADAT IBUPROFEN : STUDI GELLING AGENT DAN SENYAWA PENINGKAT PENETRASI Nurahmanto, Dwi Mahrifah, Ifa Rosi Azis, Rani Firda Nur Imaniah Rosyidi, Viddy Agustian ABSTRACT This study aims to determine the effect of using gelling agent and chemical penetration enhancer on the solid dispersion Ibuprofen gel in increasing the transdermal drug penetration. Inhibition of the COX-1 enzyme caused by ibuprofen in oral administration can cause side effects of gastrointestinal disorders, dyspepsia, diarrhea, upper gastrointestinal infections, nausea and bloating, resulting in a topical route to reduce side effects. The gel is prepared using hydroxy propyl methyl cellulose (HPMC) and carbopol® as gelling agents, and also propylene glycol and glycerin as chemical penetration enhancer compounds. The gel evaluation are viscosity, pH, spreadability and penetration flux rate. The value of the formula 3 penetration flux is 1.5383 ± 0.029 ug / cm2.minute, the formula 1 is 1.403 ± 0.055 ug / cm2. minute, the formula 2 is 0.756 ± 0.071 ug / cm2 minute, while the formula 4 is 0.5404 ± 0.106 ug / Cm2. minute. The amount of gelling agent concentration and chemical penetration enhancer compound effect on the value of the flux penetration Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-06-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/97 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung; 96-105 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 1 (2017): Jurnal Ilmiah Manuntung; 96-105 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/97/86 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/98 2021-01-31T07:57:08Z jim:ART

PERBEDAAN KECEMASAN ANAK USIA PRASEKOLAH PADA TINDAKAN INJEKSI DENGAN DITERAPKAN DAN TANPA DITERAPKAN PEMAKAIAN ROMPI BERGAMBAR DI RUANG MELATI RSUD ABDUL WAHAB SJAHRANIE SAMARINDA Sureskiarti, Enok Brutu, Marwah Maawiyah Nur Karina Children with painful procedures tend to exhibit negative behavioral reactions, such as children becoming more aggressive and uncooperative or hostile, and if these conditions continue to develop growth disturbances, it also complicates the implementation of medical procedures such as injecting drug. To know the difference of pre-school age anxiety at injection action by applied and without applying the wearing picture vest in Melati Room of RSUD Abdul Wahab Sjahranie Samarinda. This study used quasi experimentalposttest design only non equivalent control group. Anxiety was measured using the Children's Fear Scale measurement scale. The sample of the study was 30 children divided into groups of intervention and control. Analysis to see the effect between the two variables using Mann Whitney test. The frequency distribution of anxiety in the intervention group and the control group each had an average score of 0.64 (95% CI = 0.32-1.01) and 2.57 (95% CI = 1.50-3, 16). The result of this study was Mann Whitney's 0,003 (α = 0,05) analysis, indicating a difference between the intervention group and the control group. The results of mean difference analysis in the intervention and control group showed that there were differences in pre-school age anxiety at the injection action by applied and without applying the picture vest in the Melati Room of RSUD Abdul Wahab Sjahranie Samarinda. The use of pictured vests can be used as an effort to decrease children's anxiety at the injection action. Sekolah Tinggi Ilmu Kesehatan Samarinda 2017-06-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/98 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 1 (2017): Jurnal Ilmiah Manuntung; 106-115 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 1 (2017): Jurnal Ilmiah Manuntung; 106-115 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/98/87 Copyright (c) 2017 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/117 2021-01-31T07:48:07Z jim:ART

EFEK BIOLARVASIDA NYAMUK Aedes aegypti DARI GRANUL EKSTRAK DAUN JERUK NIPIS (Citrus aurantifolia) Mangampa, Yunita Nisa, Michrun Fahimah, Nurul Rannu, Sriwanti Lisu Anugrawan, Muh Doa, Febi Rofina Dengue Haemorrhagic Fever (DHF) is still one of the problems in Indonesia. Natural materials that has the property of killing the mosquito vector one of them is a lime leaf. lime leaf extract contains limonoids compounds that serve as larvacide.Tujuan of this research is to make granule extract lime leaf (Citrus aurantifolia) which has the ability as a mosquito killer biolarvacide. This type of research is a laboratory experiment. The population in this study were all three instars of Aedes aegypti larvae aged 3-4 days. The results showed that there was granule effect of lime leaf extract (Citrus aurantifolia) to the death of Aedes aegypti mosquito larvae. The granule concentration of lime leaf extract (Citrus aurantifolia) which is effective in killing Aedes aegypti mosquito larvae is 15% extract concentration formulated in granule form with percent mortality of 76.7% larvae. Sekolah Tinggi Ilmu Kesehatan Samarinda 2018-01-23 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/117 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung; 116-121 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 2 (2017): Jurnal Ilmiah Manuntung; 116-121 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/117/90 Copyright (c) 2018 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/118 2021-01-31T07:48:20Z jim:ART

EFEKTIVITAS EDUKASI UNTUK MENINGKATKAN PENGETAHUAN MASYARAKAT DALAM PENANGANAN RINITIS ALERGI Lorensia, Amelia Sari, Nina Purnama Allergic rhinitis is a common disorder of the breathing that can affect one's productivity and shock. Therefore it is necessary knowledge in self-management to eliminate exposure to allergens that can increase the symptoms of allergic rhinitis. The purpose of this study is to determine the effectiveness of education in improving public knowledge about drugs allergic rhinitis. The research method is experimental pre-sampling with adult sampling through purposive sampling. Measurement of experience conducted for 3 times, ie before getting education (pre test), post-education (post test), and one month after received education (follow up test). The research conducted in May-July 2016, involving 30 people. The results showed that there were significant differences between pre test and post test (0,000 <p (0.05)) and between pre test and follow-up test (0.000 <p (0,05)). However, no changes occurred between post test and follow up test. So education is effective in improving public knowledge in the treatment of allergic rhinitis. Sekolah Tinggi Ilmu Kesehatan Samarinda 2018-01-23 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/118 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung; 122-132 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 2 (2017): Jurnal Ilmiah Manuntung; 122-132 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/118/91 Copyright (c) 2018 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/119 2021-01-31T08:37:50Z jim:ART

EFEK EKSTRAK ETANOL DAUN SINGKONG (Manihot Utilissima Pohl) SEBAGAI OBAT ALTERNATIF ANTI REMATIK TERHADAP RASA SAKIT PADA MENCIT Rikomah, Setya Enti Elmitra, Elmitra Yunita, Diana Gustina Medicinal plants used for generations one of which is crop cassava leaves. Cassava leaves is believed to cure rheumatism, gout, anemia, constipation, and to increase endurance. This study aims to determine the Effects Of Ethanol Leaf Extract Singkong (Manihot Utilissima Pohl) As Drug Alternatif Antirheumatic Of Pain On Mice. This study was an experimental study using 25 mice. These animals were divided into five groups where each group consisted of 5 mice. Cassava leaf extracts as a control test, flamar gel as a positive control, and distilled water as a negative control. Observations were made for 45 minutes using a hot excitatory response in the form of a decrease in a lick or jump after the treatments. The results showed a decline in the response of mice to lick the feet or jump to the heat stimuli were administered after administration of cassava leaf extract. Cassava leaf extract has an effect antirheumatic to pain in mice. Based on the analysis of SPSS best dose in this study is the first dose (0.65mg / 20gr mice BB). Sekolah Tinggi Ilmu Kesehatan Samarinda 2018-01-23 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/119 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung; 133-138 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 2 (2017): Jurnal Ilmiah Manuntung; 133-138 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/119/92 Copyright (c) 2018 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/120 2021-01-31T07:48:50Z jim:ART

TINGKAT PENGETAHUAN PENGGUNAAN OBAT BEBAS DAN OBAT BEBAS TERBATAS UNTUK SWAMEDIKASI PADA MASYARAKAT RW 8 MOROBANGUN JOGOTIRTO BERBAH SLEMAN YOGYAKARTA Hidayati, Ana Dania, Haafizah Puspitasari, Murtyk Dyahajeng Currently, there are developed illnesses that encourage humans to do their own alternative medication. In 2002, an estimated shows that 92% of people in the world choose the alternative medication namely self medication, by using over the counter medicine including free and limited, however the level of knowledge in using this medication is still poor, then it is possible to make a mistake. Therefore, this research aims to find out the level of knowledge in using over the counter medicine including free and limited for self medication of society in RW 08, Morobangun, Jogotirto, Berbah, Sleman, Yogyakarta. This study belongs to descriptive observational to find out the subject characteristic, the level of knowledge and the description of the kind of medicine used by society of RW 08 Morobangun. The sample used in this study is the people who lived in Rw 08 Morobangun, Jogotirto, Berbah, Sleman, Yogyakarta. The data was taken from the interview with the patient by using the questionnaire. The sample collecting technique was nonrandom sampling and the method was accidental sampling with the number of the respondents were 175. The result showed that 175 respondents in RW 08 Morobangun, Jogotirto, Berbah, Sleman, Yogyakarta used self medication of over the counter medicine including free and limited only for their ailment. The level of knowledge in using over the counter medicine including free and limited for self medication of society in RW 08 Morobangun, Jogotirto, Berbah, Sleman, Yogyakarta showed that 42.9% reached the good category and 57,1% reached the sufficient category of 175 respondents. The conclusion of this study is the level of knowledge in using over the counter medicine including free and limited for self medication of society in RW 08 showed that most of the respondents achieved the sufficient category with 100 respondents (57,1%). Sekolah Tinggi Ilmu Kesehatan Samarinda 2018-01-23 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/120 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung; 139-149 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 2 (2017): Jurnal Ilmiah Manuntung; 139-149 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/120/93 Copyright (c) 2018 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/121 2021-01-31T07:49:06Z jim:ART

PENGETAHUAN DAN PERSEPSI APOTEKER TERHADAP SISTEM PELAPORAN MONITORING EFEK SAMPING OBAT (MESO) DI APOTEK WILAYAH KOTA YOGYAKARTA Ulfah, Sarah Ristiono, Hendy Perwitasari, Dyah A The importance of pharmacovigilance activity is the Adverse Drug Reaction (ADR) reporting system. Many pharmacists who do not report ADR incident and number of ADR indicated that more knowledge and good perception of ADR is needed. This study was aimed at investigating the knowledge and perception of pharmacists towards the ADR reporting system of Community Pharmacists in Yogyakarta City, Indonesia. Cross sectional study design was conducted to community pharmacists (n=275) in Yogyakarta City, Indonesia on the period of November 2016 to March 2017. All data were analysed by Statistical Package for Social Sciences (SPSS) software V.16.0. Results were reported as frequency, and we used cross tabulation. The questionnaire consisted of questions about the sociodemographic characteristics of the Pharmacists. Furthermore, questionnaire with nine and eight points for assessing knowledge and perception about ADR Reporting System in Indonesia was used. The response rate of community pharmacists reached 36% (n = 100). A majority of the respondent was female (81%) and respondents of age group 20–30 years were predominantly (55%). Most of the respondents was graduated as pharmacist (85%), in the graduation year of 2010-2016 (55%). Most of the pharmacist had 1-5 years of work experience (44%) and never get pharmacovigilance training (86%). Most of the pharmacists had fair knowledge ( 40%) and fair perception (65%) towards the ADR reporting system. Pharmacovigilance training and last education of community pharmacists could influence the pharmacists’ knowledge (p: 0.00 and 0.013, respectively). Moreover, there was no significant association between pharmacists’ knowledge and perception (p > 0.496). Sekolah Tinggi Ilmu Kesehatan Samarinda 2018-01-23 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/121 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung; 150-157 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 2 (2017): Jurnal Ilmiah Manuntung; 150-157 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/121/94 Copyright (c) 2018 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/122 2021-01-31T07:49:19Z jim:ART

IDENTIFIKASI BAKTERI AIR MINUM ISI ULANG DARI DEPOT YANG MENGGUNAKAN SUMBER AIR NON PDAM DI KOTA SAMARINDA Aulia, Nur Maulida Sudrajat, Sudrajat Kusumawati, Eko This aim of the present work is to know the type and the number of contamination in drinking water refill from depot using Non-PDAM water resource in Samarinda City. The sample were obtained from five subdistricts such as North Samarinda, Sambutan, Palaran, Loa Janan Ilir and Samarinda Ilir. Identification of bacteria using PCA (Plate Count Agar) media, BA (Blood Agar) and MCA (Mac Conkey Agar). Potentially pathogenic colonies tested for biochemical include SIM (Sulfid Indol Motile), SC (Simon Citrate), MR (Methyl red), VP (Voges Proskauer), TSIA (Triple Sugar Iron Agar), Nitrate, Urea, PAA (Phenyl Alanin Agar) and Glucose of. The results show that there is bacterial contamination in drinking water refill from depot using Non-PDAM water resource such as genus Staphylococcus, Klebsiella and Acinetobacter. The number of bacterial contamination were found at least in samples C1 and C2 from Sambutan, sample D2 from Palaran and the most contamination number was found in sample A1 from North Samarinda. Sekolah Tinggi Ilmu Kesehatan Samarinda 2018-01-23 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/122 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung; 158-165 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 2 (2017): Jurnal Ilmiah Manuntung; 158-165 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/122/95 Copyright (c) 2018 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/123 2021-01-31T07:49:32Z jim:ART

EKSTRAK KULIT BUAH NAGA MERAH (Hylocereus Polyrhizus) SEBAGAI ANTIOKSIDAN DALAM FORMULASI SEDIAAN LOTIO Yanty, Yuska Novi Siska, Vetria Ade Dragon fruit is a kind of cactus tree from the family Cactaceae. Red dragon fruit contains lots of vitamin C, vitamin E, vitamin B1, B2, and B3. These vitamins can increase energy, and metabolize food, and even improve skin quality. This study aims to determine whether red dragon fruit skin extract can be made into lotion preparation and to know the effect of variation of red dragon fruit skin extract on physical properties of lotio. Red dragon fruit skin was extracted by maceration, lotio was made using formulation with variation of dragon fruit skin extract which were F1 (3%), F2 (5%), F3 (7%). The lotio was making by mixing the oil phase into the water. Physical test results showed there was organoleptic change in F1, F2 and F3 after observation for 4 weeks. The average result of pH test for four weeks was meet the lotio requirements ranging from 4.5-8. F1 with an average of 6.5, F2 with an average of 7.25, F3 with an average of 7.5. The result of viscosity test is F1 0,5 poise, F2, F3 and F4 0 poise. The result of F1 7.0 cm, F2 7,1 cm and F3 7.5 cm. The irritation test results are not irritating on the use of F1, F2 and F3. The test results showed that F0 and F1 are more favorable. The result of this research was that red skin dragon fruit extract can be made into lotio formulation and there was influence of variation of extract concentration on the physical properties of lotio. Sekolah Tinggi Ilmu Kesehatan Samarinda 2018-01-23 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/123 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung; 166-172 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 2 (2017): Jurnal Ilmiah Manuntung; 166-172 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/123/96 Copyright (c) 2018 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/124 2021-01-31T07:49:44Z jim:ART

KADAR ASAM URAT PADA PASIEN TUBERKULOSIS DENGAN TERAPI OBAT ANTI TUBERKULOSIS (OAT) DI PUSKESMAS CEMPAKA MARET 2017 Nafila, Nafila Haqiqi, Rizqia Nurul Wahyunita, Sari Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis that mostly attacks the lungs. Uric acid is the result of purine metabolism in the body. Actually, uric acid is a natural substance in the body but it becomes unnatural in the body when uric acid becomes up and beyond normal limits. The purpose of this study was to detemmine the description of uric acid levels in tuberculosis patients with anti tuberculosis drug therapy (OAT) at Puskesmas Cempaka. The population in this study was 22 patients with TB patiens who received OAT treatment. The sample of this research is 15 people with purposive sampling method. Examination was done in area of cempaka with capillary blood using rapid test method. Of the 15 patient studied with pulmonary tuberculosis who consumed OAT in Cempaka Puskesmas work area, obtained uric acid levels increased (26,67%) and normal levels uric acid (73,33%) in male gender (75%) and female gender (25%). Characteristics of age in the age group 41-50 years (25%), age 51-60 years (25%) In female gender. Should be monitored specifically for the symptoms of side effects of Anti Tuberculosis (OAT) by looking at clinical symptoms, such as nausea, vomiting, etc. Sekolah Tinggi Ilmu Kesehatan Samarinda 2018-01-23 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/124 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung; 173-177 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 2 (2017): Jurnal Ilmiah Manuntung; 173-177 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/124/100 Copyright (c) 2018 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/125 2021-01-31T07:50:06Z jim:ART

EVALUASI TINGKAT KEPATUHAN PENGGUNAAN OBAT ANTIHIPERTENSI PADA PASIEN PENYAKIT GINJAL KRONIK LANJUT USIA Fajriansyah, Fajriansyah Nisa, Michrun Chronic Kidney Disease (CKD) is a condition of kidney damage that occurs for 3 months or more in the form of structural or functional abnormalities of the kidney with or without decrease in Glomerular Filtration Rate which manifests as a pathological disorder. Treatment of CKD is closely related to medication adherence that determines a successful treatment, but patient treatment adherence is often low especially in regularity for drug use. This study aims to evaluate the level of adherence to the use of CKD patient drug at the General Hospital of Education Hasanuddin University. The research design is descriptive analysis with Cross Sectional. The data were collected by using questionnaires containing questions that led to patient characteristics, medication adherence, and factors affecting drug use. Measurement of adherence used is Modified Morisky Scale (MMS) which then analyzed using Case Management Adherence Guidelines (CMAG) against 45 subjects. The result of the research is the level of patient compliance based on quadrant level 1 as many as 8 patients (17,78%), quadrant level 2 as many as 8 patient (17,78%), level 3 quadrant 17 patient (37,77%), and quadrant level 4 of 12 patients (26.66%). Sekolah Tinggi Ilmu Kesehatan Samarinda 2018-01-23 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/125 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung; 178-185 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 2 (2017): Jurnal Ilmiah Manuntung; 178-185 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/125/98 Copyright (c) 2018 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/126 2021-01-31T07:50:24Z jim:ART

EFEK HIPOTENSIF DARI ACEi DAN ARB PADA PASIEN DIABETES MELLITUS DAN HIPERTENSI DI RSUD. ABDUL WAHAB SYAHRANIE SAMARINDA Helmidanora, Rusdiati Sentat, Triswanto More than two-thirds of patients with type 2 diabetes also experience hypertension whose development coincides with hyperglycemia, where each disease has a tendency to influence the increased risk of other diseases. Sundry new guidelines, such as the National Joint Committee 8, the American Diabetes Association recommend blood pressure targets in the diabetic population of <140/90 mmHg to reduce cardiovascular risk and prevent the progression of nephropathy. This study aims to determine whether there is a difference in achieving blood pressure target < 140/90 mmHg according to Join National Committee 8 between ACEi and ARB in patients with type 2 diabetes with hypertension. This research was conducted using a retrospective at internist clinic of Abdul Wahab Syahranie hospital, by taking secondary data from the medical record from blood pressure o 49 outpatients received a single antihypertensive either drug ACEi 29 people or ARB 34 people. This study showed that the achievement of target blood pressure by <140/90 mmHg (JNC 8 guideline) between ACEi 7 (28%) and ARB 5 (20,8%) group and it can be concluded that between ACEi and ARB drugs(P=0.5) there was no differsignificantly in achievement blood pressure target on type 2 diabetes with hypertension. Sekolah Tinggi Ilmu Kesehatan Samarinda 2018-01-23 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/126 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung; 186-191 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 2 (2017): Jurnal Ilmiah Manuntung; 186-191 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/126/99 Copyright (c) 2018 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/127 2021-01-31T07:50:39Z jim:ART

EFEKTIVITAS MINYAK ATSIRI KULIT JERUK BERGAMOT (Citrus bergamia) DALAM MASKER GEL PEEL-OFF SEBAGAI ANTI BAKTERI Staphylococcus aureus ATCC 29213 Cahyani, Intan Martha Artiyani, Retno Staphylococcus aureus is a bacterial strain that causes acne. Linalool and limoneneis are the ingredients of Citrus bergamia essensial oil which has antibacterial activity Staphylococcus aureus. This research aimed to examine the effective consentration of Citrus bergamiaessensial oil as antibacterial Staphylococcus aureus ATCC 29213. Citrus bergamia essensial oil is made in series a concentration of 1%, 2% and 3% for testing of antibacterial activity using the pitting diffusion method. Based on the test results of antibacterial activity gained an average diameter of inhibitory zone Citrus bergamiaessensial oil in a row 1,151 cm; 1,529 cm; 1,683 cm. The statistically test results showed significant difference in the antibacterial activity of Citrus bergamiaessensial oil in concentrations 1%, 2% and 3% to the growth of Staphylococcus aureus ATCC 29213. Citrus bergamiaessensial oil has effective concentration 3% as stapgylocuccus aureus antibacterial and made peel-off gel mask formula. Test of antibacterial activity obtained resistibility zone diameter 1,259 cm. The result of t-test indicated that the Citrus bergamiaessensial oil peel-off gel mask has significant affect on antibacterial activity of Citrus bergamiaessensial oil. Sekolah Tinggi Ilmu Kesehatan Samarinda 2018-01-23 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/127 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung; 192-196 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 2 (2017): Jurnal Ilmiah Manuntung; 192-196 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/127/101 Copyright (c) 2018 Jurnal Ilmiah Manuntung

oai:ojs.jurnal.akfarsam.ac.id:article/128 2018-01-23T14:09:03Z jim_akfarsam:ART

oai:ojs2.jurnal.stiksam.ac.id:article/129 2021-01-31T07:50:58Z jim:ART

OPTIMASI POLIVINILPIROLIDON DAN CARBOPOL PADA SEDIAAN PATCH DISPERSI PADAT PIROKSIKAM Nurahmanto, Dwi Sabrina, Friska Wira Ameliana, Lidya Piroxicam, a non steroidal anti inflammatory drugs (NSAID), is an oxicam derivative which can be used for treatment of various rheumatic diseases, such as rheumatoid arthritis and osteoarthritis. Piroxicam patch is an affective approach evading piroxicam’s side effect such as peptic ulcer and first pass metabolism. One of the patch components is polymer that the function is to control the speed of drug release from the patch. The aims of this study were to determine the optimum formula of a combination of polyvinylpyrolidone (PVP) and Carbopol to % moisture content (MC) and the flux release in solid dispersion piroxicam patch using Simplex Lattice Design. Piroxicam was prepared in the form of a solid dispersion in PEG 4000 to increase its solubility. The design formula of solid dispersion piroxicam patch made with the ratio PVP : Carbopol, that were 1 : 0; 0.5 : 0.5; 0 : 1. The optimum formula was chosen with the ratio PVP : Carbopol, 1: 0, which gave the best result of % MC and flux release. The result of % MC was 6.91% and the result of flux release was 35.543 µg/cm2.menit1/2. Sekolah Tinggi Ilmu Kesehatan Samarinda 2018-01-23 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/129 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung; 197-206 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 3 No. 2 (2017): Jurnal Ilmiah Manuntung; 197-206 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/129/103 Copyright (c) 2018 Jurnal Ilmiah Manuntung

oai:ojs2.jurnal.stiksam.ac.id:article/134 2025-04-14T07:55:24Z jim:ART

GAMBARAN PENGGUNAAN ANTIBIOTIK PADA PASIEN PEDIATRI INFEKSI SALURAN PERNAPASAN AKUT (ISPA) DI KLINIK SINT. CAROLUS BENGKULU Rikomah, Setya Enti Novia, Devi Rahma, Septiana Antibiotics and infections are the most common problems faced by developing countries, including in Indonesia. Indonesia's awareness of the use of antibiotics rationally declines. Acute respiratory infections ranks first in terms of infant and under five mortality in developing and developing countries. This research was conducted to see the description of the use of antibiotics in patients with ISPA in Clinic Sint Carolus Bengkulu from January to December 2014. Data analysis was done by descriptive analysis with a retrospective method. The sample calculation was done by using the Slovin formula obtained by 100 samples. Of the 100 samples of this study, 57% of men and 43% of women, the age classification of acute respiratory infection was 0% of neonatal patients, 25% of infants, 32% of infants, 20% of children under five, and 23% of children, most antibiotics commonly used with ISPA is cefadroxil 60% amoxicillin 36% and erythromycin 3%, combination of TMP (trimethoprim) and SMZ (sulfamethoxazole) 1%. The type of ISPA that attacks is ISPA non pneumonia in the form of cough and cold based on medical record data at the Sint Carolus Clinic and the patient obtains the drug with a dose in safe range. Sekolah Tinggi Ilmu Kesehatan Samarinda 2018-05-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://jurnal.stiksam.ac.id/index.php/jim/article/view/134 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol 4 No 1 (2018): Jurnal Ilmiah Manuntung; 28-35 Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan; Vol. 4 No. 1 (2018): Jurnal Ilmiah Manuntung; 28-35 2477-1821 2443-115X eng https://jurnal.stiksam.ac.id/index.php/jim/article/view/134/108 Copyright (c) 2018 Jurnal Ilmiah Manuntung 36367fbcf89ebe1297631682866fc4ab