ANALISIS EFEKTIVITAS BIAYA TERAPI KOMBINASI CANDESARTAN-AMLODIPIN DIBANDINGKAN DENGAN RAMIPRIL-AMLODIPIN PADA PASIEN HIPERTENSI RAWAT JALAN DI RS X KOTA SAMARINDA

Abstract

Hypertension or high blood pressure is one of the degenerative diseases that require long treatment even for a lifetime.  Treatment therapy for hypertensive diseases is carried out over a long period of time so that it requires considerable costs and the effectiveness of different antihypertensive therapies. The purpose of this study is to find out the cost effectiveness of combination treatment therapy between candesartan-amlodipine drugs compared to ramipril-amlodipine drugs in outpatient hypertension patients at Hospital X Samarinda City in 2020. The design of this study was conducted cross sectional. The data in this study were taken retrospectively. Sampling is done with total sampling. The data is analyzed statistically using SPSS application with Mann-Whitney test. In this study, the number of hypertensive patients who met the inclusion criteria was 55 patients, for patients with candesartan-amlodipine combination therapy as many as 31 patients while ramipril-amlodipine therapy as many as 24 patients. The results showed that the percentage of the therapeutic effectiveness of drug candesartan-amlodipine by 61,29% and the drug ramipril-amlodipine was 58,33%. The candesartan-amlodipine therapy group was more cost-effective with an ACER (Average Cost-Effectiveness Ratio) value of Rp. 4.932,27 compared to the ramipril-amlodipine therapy group with an ACER value of Rp. 5.575,64 in outpatient hypertension patients at Hospital X Samarinda City in 2020.